Ladies and gentlemen, thank you for standing by. Welcome to the Royalty Pharma Fourth Quarter 2020 Financial Results Conference Call. I would now like to turn the call over to George Grofik, Senior Vice President, Head of Investor Relations and Communications. Please go ahead, sir.

Thank you, operator, and good morning and good afternoon to everyone on the call. Thank you for joining us to review Royalty Pharma's fourth quarter results. You can find the slides to this call on the Investors page of our website at royaltypharma.com. Moving to Slide 3, I would like to remind you that information presented in this call contains forward-looking statements that involve known and unknown risks, uncertainties and other factors that may cause actual results to differ materially. I refer you to our S-1, Prospectus on file with the SEC for a description of these risk factors. And with that, please advance to Slide 4. Our speakers on the call today are; Pablo Legorreta, Founder and Chief Executive Officer; Jim Reddoch, EVP, Co-Head of Research and Investments and Chief Scientific Officer; Marshall Urist, EVP, Co-Head of Research and Investments and Terry Coyne, EVP, Chief Financial Officer. Pablo will discuss the key highlights after which Jim and Marshall will provide an update on our royalty acquisitions. Terry will then review the financials. And after concluding remarks from Pablo, we will hold a Q&A session. Chris Hite, our Vice Chairman will also join the Q&A session. And with that, I'd like to turn the call over to Pablo.

Thank you, George and welcome to everyone on the call. 2020 was truly a landmark year for Royalty Pharma. I want to start by focusing on highlights of incredible year for our company. First, we strengthened our capital base and our access to the future capital through our successful IPO and bond offerings. With our balance sheet strengthened, and with our ability to rapidly delever, we're in a very strong position to execute our strategy. Second, we further expanded our royalty portfolio with eight announced acquisitions, totaling 2.4 billion, maintaining our market leadership and enhancing the outlook for our adjusted cash receipts. This royalty transaction spanned multiple therapy areas, but have one thing in common, they are associated with potentially transformative medicines, and we're very optimistic about their patient benefit as well as their commercial value. Terry will discuss how this impacts our long-term outlook later on, on the call. And lastly, we have navigated this complex and busy year while delivering double-digit bottom-line growth and building the organization to strengthen our market leading position. We have made a number of senior level hires, expanded our board of directors and started an important new strategy and analytics initiative. On Slide 7, you can see our financial results for the fourth quarter and full year. In the fourth quarter, we delivered 9% growth in adjusted cash receipts, our top line and 22% growth in adjusted cash flow, which is our bottom line. This excellent momentum puts us in a great position to deliver another year of strong performance in 2021 as Terry will discuss in a bit. For the full year, our top line growth was 1% and bottom-line growth was 15%. When thinking about our adjusted cash receipts growth, keep in mind that we had a large payment for Tecfidera in 2019, which affected year-over-year comparisons in the first quarter, but has no further impact. Excluding Tecfidera our adjusted cash receipts would have grown at 9% for the full year. So overall, I am delighted with our progress in 2020. And we're very confident in our long-term outlook. With that, I will hand the call over to Jim and Marshall to update you on our royalty portfolio.

Thank you, Pablo, and good morning and good afternoon everyone. As shown on Slide 9, 2020 was a record year for biopharma royalty funding. Based on our market intelligence, we believe that there were 23 major royalty transactions in the year with a combined value of $5.4 billion. Inevitably, there is some volatility in the trends from year-to-year. However, as an indicator, the 2020 transaction count and value figures are more than double the average of the preceding five years, and each represent record highs. In short, the market is growing significantly, and we are confident that the tailwinds supporting this growth will continue for the foreseeable future. These tailwinds include the fast-growing demand for capital from the biopharma industry, the extraordinary pace of innovation taking place across the entire life science ecosystem and the secular trends driving increased biopharma market sales. Slide 10 illustrates our transaction funnel in 2020. During the year we reviewed more than 265 potential transactions. This in turn led to around 70 CDAs being signed and 38 proposals being submitted. Ultimately, we announced eight transactions for a total value of $2.4 billion. The math shows that we transacted on just 3% of the royalty opportunities we initially reviewed. This speaks to both our ability to execute on promising royalty opportunities and to the intense level of scientific diligence and financial discipline we apply in the process. The rigor of our approach is part of our unique skill set, and is a key reason why Royalty Pharma has delivered and continues to deliver attractive returns to our investors. Slide 11 provides an overview of the eight transactions I just referenced. We are excited that these encompass a range of transformative therapies across five therapeutic areas. Of the 12 royalty bearing products included in these transactions, nine were for approved therapies and three were for development stage therapies at the time the deals were signed. The products we added to the portfolio spanned five therapeutic areas, including rare disease, cancer, neurology, GI and infectious disease. This speaks to the unique approach that we take in adding high quality assets to our portfolio regardless of therapeutic area. One notable development stage deal that we completed in 2020 was for the exciting SMA drug Evrysdi. Around a month after we acquired this royalty, Evrysdi was subsequently approved and launched by Roche, again, underscoring the high level of due diligence that we apply in our process. Looking ahead, the street expects a number of these medicines to become blockbusters in the next several years. And we estimate based on consensus analysts forecast that these transactions will add more than $400 million to our adjusted cash receipts by 2025. And with that, I will hand the call over to Marshall.

Thank you, Jim and hello to everyone this morning. Turning to Slide 13, let me start by highlighting that 2020 was a strong year in terms of the scale of royalty acquisition, and builds up the similarly strong year in 2019. In fact, if we look over the past two years, we announced 14 transactions totaling approximately $5 billion. As a result, we have significantly expanded our portfolio of innovative therapy with long duration patents, further diversifying our revenue mix and we are confident that we will generate returns consistent with our targets. On this slide, you see a summary of our recent portfolio additions since last quarter's call, adding one approved product and two development stage therapies. In December, we acquired a royalty from BioCryst, Orladeyo, the first oral therapy for hereditary angioedema. Orladeyo was recently approved in the US and Japan and a European approval decision is expected in the second quarter of this year. As an oral agent, we believe Orladeyo will expand options for patients, bringing greater convenience and potentially expanding the use of prophylaxis in this serious disease. The $125 million we provided to BioCryst will be used to support the launch of Orladeyo, as well as to fund development of their oral Factor D inhibitor BCX9930 and complement mediated diseases. In return, Royalty Pharma is entitled to 8.75% of sales of Orladeyo up to $350 million, with step downs above this up to $550 million. We will also receive a 1% royalty on sales of BCX9930 if commercialized. We look forward to seeing the progress of BCX9930 during 2021. This is a great example of the type of non-dilutive deal structure we're able to offer to our partners, in this case to a biotechnology company to facilitate pipeline expansion and the transition to a commercial company. Now moving to our most recent portfolio addition, we announced in January the acquisition of Minerva Neurosciences royalty interest in Seltorexant. A compound which is in Phase III development by Johnson & Johnson for the treatment of major depressive disorder with insomnia symptoms, in return for an upfront payment of $60 million and up to $95 million in additional milestone payment. We're entitled to receive a mid-single digit royalty on worldwide sales of Seltorexant. We are very excited by this opportunity as Seltorexant is potentially the first medicine to address this important unmet need in patients suffering from depression. And while this is the therapy that potentially fits at the higher end of the clinical rich spectrum for us, our extensive due diligence provided significant comfort on this clinical profile based on strong proof of concept data to date. This included four placebo and active controlled efficacy trials that demonstrated consistent safety and efficacy. So to summarize; two very different partners which take us into new therapeutic categories and each with the potential to bring important innovation to patients. And with that, I'll hand it over to Terry.

Thanks, Marshall. Let's move to Slide 15. We had another good quarter with total royalty receipts of 9% compared to last year's fourth quarter on a pro forma basis. On a full year basis, growth of 2% reflected our final receipt associated with Tecfidera of $150 million in the first quarter of 2019. As you can see royalties from our largest franchise cystic fibrosis grew 37% this quarter and 30% for the full year, driven by the strong launch of Trikafta in the US and Kaftrio in the EU. Imbruvica, Xtandi and Promacta also contributed strong double-digit growth, both for the quarter and on a full year basis. Slide 16 shows how our royalty receipts translated to strong adjusted cash flow in the quarter. As you're aware, adjusted cash receipts is a key non-GAAP metric for us, which we arrive at after deducting non-controlling interest. This is what we view as our top line, and it amounted to $484 million in the quarter representing growth of 9% compared with last year's fourth quarter on a pro forma basis. When we move left to right, operating and professional costs of $50 million, equated to 10.4% of adjusted cash receipts. This was somewhat below the level of the third quarter, which included certain expenses related to our IPO and bond offering. R&D funding remained at a relatively low level and substantially lower than in the year ago quarter, given larger ongoing development stage funding payments in 2019. Net interest of just $1 million was sharply lower as it reflected the debt refinancing and a shift to semiannual interest payments arising from our bond offering. The next interest payment will be in March of this year. Interest paid in Q4 would have been $33 million if our interest payments were paid quarterly instead…

Thanks Terry. Let me quickly close by saying that I'm more confident than ever that Royalty Pharma is well positioned to continue our leadership of the rapidly growing market for biopharma royalty funding. With our strong 2021 outlook and our raised long-term guidance, we have many exciting years ahead. This is a remarkable time in the history of our industry, with incredible innovation and groundbreaking therapies that are changing the lives of patients globally. Royalty Pharma is uniquely positioned as a levered play on the innovation in life sciences. With that, I would like to open the call to Q&A, back to you George.

Thank you, Pablo and operator we'll now open the call to your questions. Operator, please take the first question.

Thank you. [Operator Instructions] Our first question comes from Steve Scala with Cowen. Your line is open.

Thank you very much and congratulations on a great 2020. For deals that Royalty Pharma considered but did not do in 2020, what was the most frequent reason? Was Royalty Pharma not sufficiently comfortable with the risk involved? Did a competitor offer more attractive economics? Or was there some other reason? I assumed risk in economics always go hand in hand, so how do you know you have the optimal balance? And how might that balance change in 2021? Thank you.

Sure, Steve. So I'm going to ask Jim to add to maybe some initial remarks, but I think as you probably have heard us already explain in the past, a lot of sort of the thing that drives our evaluation of transactions is just a huge amount of discipline, because over two decades of investing, we've actually looked at so many things. And many of which we have passed on, and many that we've done, but also, we have the experience of transactions that we did that didn't work out. And we always try to learn from those and understand what happened that didn't - what part of the thesis was incorrect, and then try to apply that in the future. It's not always easy. It's difficult actually, to always - because what's also interesting as industry is that every opportunity is different in life sciences, right. Every product is different, the clinical program is different, the size of the market is different, the competitive landscape is different in some cases, in many cases we have unique products with very little competition, but in others, there's more competition. So there's many, many factors that we have to take into consideration. But always, discipline is key and I always tell the team, making a valid investment is very, very difficult, very painful to correct the impact of a valid investment. So it's always trying to find that balance of very attractive underlying attributes that the products have, with very attractive upside. And also understanding the downside, well, understanding where things could fail well, but Jim, do you want to add to what I just said?

Yeah. Yeah, thanks, Steve. I mean, I think that you mentioned a couple of things risk and economics and occasionally competition. But I would add to that, and it's really a mixture of all of these that in some cases the target company that we're speaking with, was acquired, or ends up getting a different flavor of financing or in some cases, is still considering our proposal and other proposals. So it just hasn't really happened yet. So it's really a mixture of all of those, but I'm really proud, I think we're all really proud of generating the 260 plus number of opportunities at the top of the funnel, and I think that's really a testament to the number of parties, both corporate and academic and otherwise that are considering royalty transactions these days, because that number is grown from the previous year and from prior years. And also that we saw 70 opportunities that were really worth going in depth on and getting confidential information and we want to be aggressive and putting proposals out there as well. So that I think that 30 plus number represents us really wanting to get term sheets out there. But in some cases, those for reasons that we're mentioning now don't end up crossing the finish line. But as Pablo says, we want to keep a very high bar for things that we ultimately transact on.

In real life Steve that what we invested in last year the $2 billion plus of transactions that we did, which is - what's great is that just looking out, this transaction will add over $400 million of revenue in the 2025 timeframe with what we believe are conservative forecasts and with a good level of predictability. So that is quite a positive outcome for us based on the things that happened last year. Thank you.

Thank you.

Thank you. Our next question comes from Geoff Meacham with Bank of America. Your line is open.

Hey, guys, thanks for the question. Just had a couple, another one on future deals, I guess the question is, there's the law of large numbers begin to apply as you continue to grow the top line, I know there are a ton of smaller deals you can do as you just highlighted on Slide 10. But I think the goal is to find perhaps another CF type of opportunity in terms of the magnitude. And then the second question is Terry, what are the longer-term considerations of a rising interest rate environment? I know - I don't know if you guys have used hedging strategies in the past, but could you deploy that going forward? Thank you.

Chris, do you want to take the first part of the question about the scale of the opportunities we see and also some potential for big deals maybe through M&A?

Sure.

And we can answer the second part.

Sure. Thanks Pablo and thanks for the question Geoff. Yeah, look, I mean, we - as Jim went through the funnel, and Pablo went through the funnel, we see a lot of opportunities. And we see a lot of ranging opportunities, right, smaller and larger. And I think even this past year we actually did a wide range of deals, right, from smaller deals to like a bigger deal around the CF and also around Evrysdi. And I think one of the things Pablo just mentioned was M&A. I think we've been actively having discussions around helping people around M&A situations and creating synthetic royalties there. And we sort of see that as an interesting opportunity, in addition to the synthetic royalties, which is also we see really sort of picking up steam. So obviously, we're looking across the spectrum for deals and they can be small or big, but we don't see a lack of opportunity out there to grow our top line.

And then, Geoff, on your question on long-term, rising rates, we were lucky that we were able to take advantage of the markets in the summer at very attractive - at a very attractive time in sort of history in terms of issuing bonds and now 100% of our $6 billion of debt is fixed. And so it's not something that we have to be as focused on in the near term. The other thing I would say is that as our bonds have traded in the market and bond investors have gotten to know Royalty Pharma better, our spreads have tightened significantly. So the spread on our 10 year, while the 10-year Treasury has increased, the spread on the 10 year is actually tightened by almost 80 basis points. So I think we feel like we're still in a great position, to the extent that rates really do see a significant uptick in the long-term, I also think that that will be reflected in asset prices and prices will be adjusted accordingly. So it is sort of a natural hedge in the way that our business works, because we're constantly reinvesting and it would be reflected in asset prices.

Okay, thanks, guys.

Thank you. Our next question comes from Chris Schott with JP Morgan. Your line is open.

Great, thanks so much for the questions. Just if I look at 2020 it was obviously a bigger year for capital deployment for the company and the broader royalty market. And I know deal flow can be choppy year-to-year, but the trend seems to clearly be moving higher here. So when I think about the longer-term guidance, I didn't want to be conservative. But is there any reason we shouldn't think about capital deployment closer to the range we saw in 2020 versus I think, the roughly 1.5 billion or so that reflecting in that guidance. I just want to see is there any rate limiting factors other than just finding attractive terms that whether it's capital structure, et cetera? And then the second question I had was just on the funnel of transactions and you've talked about a couple sources of deals whether these are SMID cap biotech M&A, academic, did you see the mix of those change at all on 2020 in favor of one of those, I guess verticals versus another or you're seeing more opportunities as we, again, think about biotech versus academic versus other sources. I'm trying to get a sense of how that's changing as the market evolves over time? Thanks so much.

Sure, Chris, thank you. And I think, in terms of the guidance, we're a brand-new public company. So we want to be conservative. But obviously, the tail winds are incredibly, incredibly strong for the industry in general. And also, for us specifically based on the service that we provide, the potential solutions that we provide to many companies that require very significant amount of capital. And I think, the sort of difficult thing to predict is - and I think there was a prior question about a deal like the CF deal that we did in 2014, which was over $3 billion, one transaction, and that year, we invested four. And I think, in our case it's not likely that it will be an academic royalty of that size or foundation royalty of that size, but where we could have a large transaction, significant transaction would be in an M&A situation, and those kinds of transactions are obviously difficult to predict. And it's not something that is sort of the bread and butter that deals that we can do every quarter, but I think over the next three to five years, it's likely that there'll be a couple of those, at least a couple, I think. And that's the more difficult variable to predict in terms of the scale of our investment over the next five years or so. But let me turn it over to Marshall now, who can provide some perspective on the funnel and where do we think deals will come from?

Thanks Chris. So to your question about the kind of mix of sources of transaction, so I don't think anything has necessarily fundamentally changed in terms of the mix of sources of transactions. Obviously, that can change year-to-year. If you look at 2020, it was a good mix. There is academic or foundation royalties there and R&D funding transaction, synthetic royalties and traditional royalties as well across the years, so there's a pretty good mix. And I think that's reflective of the underlying fundamentals of the markets we see. I think we are, as we said, before optimistic about this synthetic royalty opportunity and growing that business in the years to come with BioCryst at the end of last year being a good example. So we certainly see growth in that part of the market. But fundamentally, I think you'll continue to see a good mix of different sources of opportunities for us.

Thank you.

Thank you. Our next question comes from Greg Gilbert with Truist Securities. Your line is open.

Thank you. Going back to that funnel slide again, I was curious to what degree either companies are collections or collections of royalties, existing collections royalties factored into that funnel before or if any exists now? And curious as well, Terry, I don't know if you're willing to be more specific about what specifically changed in the updated CAGR guidance, any comments would be helpful. And lastly Pablo, I was hoping you could comment on how data science may inform your sourcing strategy going forward. Thank you.

Of course, so Jim, do you want to take the question on the funnel? And then Terry will answer the second part of the question. I'll close with a comment on data science.

Yes. Greg, correct me if I'm wrong, but I think your question was sort of how we count the number of opportunities and whether it's on sort of a per company or a per molecule basis? And I think the answer is that it's a per molecule basis. So in the case of Biohaven, last year, which included Nurtec and zavegepant that would be sort of two opportunities that we would see and I think that, increasingly in BioCryst is the same way that also included two molecules and increasingly we are seeing this positive trend that companies that we like and trust to really apply best practices developmentally and commercially have multiple assets that we're interested in. So I think that in both of those represent times where we can kind of get two interesting assets in one fell swoop. And also start to follow these assets, that earlier assets at an earlier stage, and to really get comfortable with them in an attempt to kind of grow our commitments, and our financial commitment to that product over time.

So Greg, on your question on sort of what's driving the long-term increase and our long-term outlook, I think it's a mix. So one, we had a really good year of investing in 2020. We added a number of attractive products that are going to be contributors there. That being said, a number of them were already in sort of our initial guidance that we provided back in August. But it's also the strength of our existing portfolio sort of broadly. But it's driven by in particular, CF Imbruvica, Xtandi, Tysabri has continued to perform quite well and Promacta. And then also, our outlook for some of the launching products like Trodelvy and Evrysdi. And then I think the last thing is just our confidence in the growth of the market and the tailwinds. And our ability to maintain our leadership position and continue to bring in really attractive assets, I think all of those factor in and gave us a lot of confidence that we could raise that long-term guidance, long-term outlook.

So to answer your question about the new initiative on sort of strategy and analytics, that is - a lot of it is data science. So let me just step back a little bit and explain something. So a big part of the strength of our sourcing and evaluating of opportunities over the last several decades has been the very singular focus we have on products and in life sciences. It's all about understanding product. And the strength comes from the fact that, for example, we have a team that has been working together for a very long time, I think Molly is close to 15 years and Jim also 15 years, anyway, people have been working together for a very long time and the fact that we can follow. So for example, if you look at specific therapeutic areas, multiple sclerosis, or TNFs or hematology, we follow these areas very closely, systematically, every quarter looking at products that are on the market, what they're reporting prescriptions, the trends, and talking to the prescribers regularly over and over again over years, and understanding them, understanding how they're using those drugs, and how all of that is changing. And, and then obviously, all of that effort includes also trying to understand the products that are being developed and how they're going to fit into the whole landscape and how they're going to be used and trying to then see if they're going to be important drugs, three, five, even 10 years out. Some of these drugs might have trials that read out many years into the future that could impact the later years and our investments and understanding all of that is really critical. And we've done that, we've been able to do that well at Royalty Pharma. But I think…

Thanks a lot.

Thank you. Our next question comes from Terrence Flynn with Goldman Sachs. Your line is open.

Great, thanks for taking the questions. Congrats on 2020. On the long-term guidance, I was just wondering, I know, in the past, you had mentioned that half of the growth was from existing deals and half was going to be from new deals. I'm assuming now that's maybe shifted where maybe over half is from existing deals less than half from new, so just wondering too if you could provide any incremental color there. And then a question probably for Marshall, on Trodelvy, obviously, one of the growth assets you guys have talked about longer term. What - I would love your perspective on the potential for this asset beyond breast cancer? Thank you.

Yeah. Sure, Terence. So on the guidance, yeah, so 7% to 10% is sort of the total number and as you correctly pointed out, that also includes the impact of new investments. For our base current portfolio as it stands today, we expect growth in the mid-single digits. And so the rest would come from additional investments.

Marshall?

Great. Yeah. Hi, Terence good morning. So on Trodelvy, we are really excited about that is off to a good start. And also that Gilead has recognized that value and is putting enormous resources globally behind the product. So certainly when we originally partnered with Immunomedics, the triple-negative - the late-line triple-negative breast cancer indication was our - was the core of what we were looking at. And we are optimistic about both moving earlier in triple-negative and the HR positive data, which we'll see later this year. And then the next two indications bladder and lung cancer, bladder is a competitive space, but we do think that Trodelvy has a unique kind of combination of efficacy and tolerability in that disease as well. So we are excited to see how that rolls out as well. And then all of the activity in Trop-2 positive cancers including the lung cancer opportunity are certainly intriguing and we will be eagerly awaiting how that progresses and how Gilead moves lung and other indications for it in the future.

Thank you. Our next question comes from Umer Raffat with Evercore. Your line is open.

Hi, guys, this is Mike DiFiore in for Umer. Congrats on the quarter and thanks so much for taking my question. Just two if I may, again, with regards to your updated long-term outlook, it would seem to be now more of a 60-40 organic versus inorganic contributive split. Just focusing on organic growth, what would you say would be the biggest product drivers to this mid single digit growth and how much does product pricing factor in here? And as a follow up in terms of inorganic future deal growth, is this predicated more so on riskier development stage deals in the past? And I know, you said that M&A types of deals are kind of harder to predict. And if you could spread more color on how earlier stage deals and as well as M&A stage deals could factor into this mix going forward? Thank you.

So I'll take the last part of your question and Terry can answer the first part. So I think the - if you look at what's happened over the last eight years, it turns out that it's been pretty balanced roughly half and half, I mean, maybe 55-45, between approved and unapproved and 55 approved 45 on approved. And I think over the long-term, it probably will be at similar ratio, where it could be close to evenly split. Could go maybe larger approved or maybe larger the other one, it's going to be hard to predict. But what has happened over the last couple of years is that we have invested a lot more capital on approved products. Jim mentioned that already, in his prepared remarks. But I think the unapproved opportunities for us is really big, because as we've talked multiple times in the past the biotech industry is in its sort of Golden Age. And there's so much demand need for capital among biotech's' that have been created over the last 10 years, many of which have gone public over the last five years, and raised a huge amount of capital many close to $100 billion of capital raised by biotech's in IPOs and follow ons. And all of that money, obviously, is funding early-stage trials, but these companies will need funding for the larger Phase III trials. And I think - that's where I think there's going to be very interesting opportunities for us. And I think over time, maybe the balance will shift to have a little bit more investment in unapproved maybe getting to half and half. But it's a risk, we're very happy to take because it comes with very attractive upside. And I think I would also note that we are actually having discussions today about funding they'd say swells, not only with biotech's, but with some of the bigger companies that also have very, very attractive portfolios that require so much capital that they want to actually work with a significant risk. So it is an attractive opportunity for us. It's one where, if you look at the amount of capital we have today, invested in unapproved, it's so low on a relative basis that we could invest $2 billion, $3 billion over the next two, three years in unapproved and that would probably bring it back to about a 50-50 ratio. And it's something that would be very attractive for Royalty Pharma to achieve very attractive returns for our investors. But I'll pass it on to Terry now for the other part of the question.

Yeah. So your question on sort of the growth drivers for the long-term outlook, I think, certainly, we're lucky that we have a number of products that are still in the early or middle innings of their close. So when we look across the portfolio, I think the know, the bigger drivers will still be CFs, but also Imbruvica and Evrysdi and Trodelvy and Xtandi and also Nurtec, I think we do expect all of those products to be healthy contributors and to also offset some of the explorations that we will face over the next couple of years. In terms of the mix of volume versus price, our expectation is the vast majority of growth will be driven by volume and price will be less than a factor.

One thing to just mention about just adding to what Terry said, is all of those products, I think he mentioned five or six that are just incredible drugs blockbusters, that many companies have one or two of those. We have six of this amazing drugs, with very significant growth, high - double digit growth, some are growing at 30% per year or more, because they're in their launch phases. But what's very attractive about Royalty Pharma is that the growth is driven by a diversified portfolio of blockbusters, different set of blockbusters not one, not two, but many of them. So that makes our growth much more predictable than many companies. And I think that's something that many investors have probably not appreciated enough that it is - the diversification we have helps our top line and our bottom line and makes both the top line and the bottom line fairly predictable. Anyway I'll stop there.

Great. Thanks so much.

Thank you. And our next question comes from David Risinger with Morgan Stanley. Your line is open.

Yes, thanks very much. And let me add my congrats as well. So I have two questions. First, Pablo, if you could discuss the potential for future M&A transactions, so what could they look like? And when you say M&A transactions, could you provide a little bit more color on what the company could be acquiring beyond just royalties? And then second, with respect to the comment about funding late-stage trials, obviously, Royalty Pharma has had some successes, but also a mixed track record. So how will the company ensure that it's not just taking on trials that big pharma or other biopharma companies are hesitant to fund internally? Thank you.

Yeah, so the last comment you made, made me reflect that is there are many things that we have passed on, because there was a question to Jim before of what are the some of the themes we have - why we have passed on investment. And it's in many cases is exactly what you just said, that when we have discussions with companies, often they want us to fund assets that maybe don't make the cut that they decided not to fund. And it's amazing when I reflect on the past, how many things - with big companies, medium sized companies where the asset looks great. And then when you dig in you realize that at the end, they decided not to fund that. And we ended up passing in many of those cases. So that's something that's very important for us to tease out when we're having these conversations. And in fact, what we generally try to do is to tell those companies, what we would like to do is to find the ones that you are funding the top programs in by us funding those, we're going to free up capital, that's going to let you then expand the number of opportunities that you're funding into others that might be a bit more risky. But and that's worked out relatively well in many cases. I will also add that if you look at the track record in the past the over $6 billion that we've invested in unapproved products over the last eight years, and now we're going into the ninth year, 90% of those worked out and it just happened that after we went public, we had a couple of failures with Ibrance in the sight of kinetics cardiovascular drug, but we have had maybe six…

That's great. Thanks very much.

Thank you. And I'm showing no further questions at this time. I'd like to turn the call back to Mr. Pablo Legorretta for closing remarks.

Thank you, operator and thank you to everyone on the call for your continuing interest in Royalty Pharma. My team and I look forward to continuing to share our progress with you. If you have any follow up questions, please feel free to reach out to George. Thank you for today. And we're here to continue having discussions with all of you.

Ladies and gentlemen, this concludes today's conference call. Thank you for participating. You may now disconnect. Everyone have a great day.