Douglas A. Berthiaume
Analyst · Morgan Stanley
Okay. Thank you, John. Well, 2012 was certainly a challenging year for Waters, especially in comparison to the stronger growth rates we enjoyed in 2010 and 2011. After a slower-than-expected start to the year, we recalibrated our expectations and continued to track at a pretty consistent organic growth rate through the following quarters. However, and as we have seen in previous periods of sluggish demand, pricing held up across our product line and we were able to control our expense growth. These factors were important in delivering stable levels of profitability. If you look at 2012 growth rates across our major product lines, we continued to benefit from newer core offerings in chromatography, mass spectrometry and thermal technologies. Our recurring revenues, the combination of chromatography consumables and total instrument service sales, generated consistent growth in 2012 and contributed to our overall profitability. Pharmaceutical end markets were mostly stable across the year while many industrial chemical customers, given the weaker general economic conditions, held back on capital spending. Governmental and academic spending during the year, as might have been expected, was pretty soft. Geographically, we were pleased by the relative strength of our business in Europe. At the onset of the year, the concerns that instability in smaller European Union countries would spread across the continent appeared to have been somewhat overstated. And in fact, European pharmaceutical demand remains sufficiently strong to offset the somewhat slower sales to governmental and chemical consumers. Our business in developing regions was mixed during the year. Most importantly, growth in China remained robust off a strong 2011 performance. On the other hand, a convergence of issues hampered our performance in India. Our developing market businesses in Eastern Europe, South America and Eastern Asia delivered uneven results and cumulatively performed at levels weaker than we had hoped. There are some speculation that the potentially recessionary economic conditions in the larger consuming economies, principally Western Europe and the United States, limited scientific investment growth in the more fragile export-oriented countries. We are hopeful that an outlook for moderate but stable global economic growth in 2013 will result in a recovery of spending for analytical tools in many of these developing countries. On the competitive front, we feel the landscape remain relatively unchanged in 2012. At this point, nearly all companies offering liquid chromatography systems have acknowledged the momentum toward UPLC-type separations, and we feel confident that our leadership position will allow us to continue to direct future market developments and maintain a premier market share position. Our ACQUITY H-Class instrument system continued to bridge UPLC capability to classical HPLC applications. Also on the separations technology front, we launched our UPC2 system in 2012. An industry first of its kind, UPC2 has begun to establish a new performance category in analytical instrumentation that meaningfully improves workflows across many applications. In mass spectrometry, I believe we have established a performance leading position in tandem quadrupole technology, and sales growth for our Xevo TQ-S in 2012 suggests a strengthening market position. In applications ranging from clinical drug development to food safety testing, Xevo TQ-S offers a new level of sensitivity combined with high reliability and usability. In 2012, sales of our top base instruments declined in comparison to somewhat stronger 2011 results. However, recent business activity for instruments, such as our SYNAPT HDMS and Xevo QTof systems, has improved, and we are anticipating a return to growth in 2013. Our TA Instruments division performed well in 2012. For the full year, TA's constant currency revenues were up about 8%. Following a double-digit growth performance in 2011 and in light of global economic weakness, these results are pretty impressive. High points for TA in 2012 include the continued successful integration of purchased businesses into the TA portfolio and the buildout of a discovery line of thermal analyzers and rheometers. In 2012, TA also successfully acquired new product lines and technologies to expand their business into high temperature material characterization markets. Looking at the fourth quarter, our constant currency sales grew about 1.5%, and our adjusted earnings at a moderately higher level. These results were in line with our expectations and include both the adverse impact to margins from a recently significantly weaker Japanese yen and the positive effect of a lower-than-anticipated tax rate. For the Waters division, we saw growth in our pharmaceutical end markets, significantly driven by strong demand in Europe and China, a continuation of a dynamic that we saw in the third quarter. The global combination of government and university shipments declined at a mid-single digit rate in the quarter, with weakness in academic demand most pronounced in Europe, Japan and in a few smaller countries. U.S. government and academic sales held up well with recent ordering trends suggesting stronger, high-end mass spec demand. Looking at our applied markets and focusing on food and environmental applications, we have a history of healthy but lumpy growth performance. In the fourth quarter, our global food and environmental growth was down in comparison to last year. However, the decline came as a result of strong growth in the U.S. market, offset by a more significant decline in Europe. We are encouraged to see more food testing uptake in the U.S. as we feel that this market represents a large future growth opportunity. In fact, within the last month, the U.S. Congress passed legislation sending a clear message detailing the importance of scientific training on advanced methods of analysis. This is certainly encouraging for Waters as we have actively assisted in developing such methods and training protocols in cooperation with global regulatory agencies. Our TA division finished 2012 with a strong fourth quarter performance, completing a year of profitable growth. In the quarter, constant currency sales were up 7%. TA's organic growth was primarily driven by continued global adoption of discovery thermal and rheology systems and generally strong international sales. High-temperature instrument sales also contributed nicely to the division's overall performance in the quarter, a trend that's promising for 2013. Looking at the Waters division fourth quarter sales geographically, constant currency sales growth in Europe was in line with the company's overall growth rate. European strength in biopharmaceutical markets was offset by weak academic and chemical analysis sales, including a decline in applied market instrument system sales against the tough prior year comparison. European pharmaceutical results included healthy spending from large global firms in the region. In China, our sales growth was strong and broad based in the quarter, with most major product and market segments growing at double-digit rates. The fourth quarter results in China complete a year of strong growth in a very important market for Waters. Our competitive position in China is strong, and our access to the most attractive analytical market segments within China is reflected in the sales growth and profitability we have delivered in the fourth quarter and for the full year. On the other hand, our sales in India were lighter than we had hoped as local currency weakness, recent drug manufacturing and CRO issues, combined with government inertia, have contributed to slower business momentum. We continue to believe that underlying demand for new instruments, primarily for generic drug manufacturers in India, remains strong, and we anticipate seeing improved ordering trends in upcoming quarters. We remain confident in being able to maintain a leading share position and know that in the long run, India is an important and attractive market for us. Waters division constant currency sales in Japan were moderately down in the fourth quarter as weaker industrial chemical results offset strong growth in our pharmaceutical business. We're cautiously optimistic that a recent weaker yen may stimulate more business in 2013 from our industrial chemical export-oriented customers in Japan. In the U.S., and staying on the Waters division performance, we saw the strongest growth in instrumentation for our applied markets, including food and environmental testing. A modest decline in shipments to pharmaceutical segments is largely accounted for by weaker sales to large accounts, interestingly, the same set of customers that grew nicely in Europe. Combination of government and academic business grew at a solid mid-single rate in the quarter, with increased business activity in the high-end mass spectrometry system. Now, I'll discuss some product line dynamics that we saw in the quarter. Our recurring revenues, the combination of service and chromatography consumables, grew at a high single-digit rate in the quarter. The growth in chromatography consumables was strongest in China and more moderate in most other regions. Sales growth of ACQUITY UPLC columns suggests a continuation of high attachment rates and of a gradual increase in UPLC technology and regulated methods. Our service business growth was more geographically balanced and close to a double-digit rate in most regions. Looking at our Waters division instrument system sales, performance was comparable for LC/MS instruments and LC instruments in the quarter, with moderate declines in sales in comparison to last year's results. For LC/MS, our strongest performing instrument systems embodied Xevo TQ-S mass spec technology combined with ACQUITY UPLC. This configuration is a workhorse tool for quantitative bioanalysis applications and drug development. And as I mentioned earlier, there are signs based on our recent ordering trends in the fourth quarter of 2012 and as we start 2013 that we are seeing improvements in our high-end top base demand. On the chromatography front, ACQUITY UPLC continued to edge into more QC applications. We believe that opportunity to see higher utilization of UPLC technology and QC application lies ahead of us. Up to this point, expansion into this segment has been limited by a combination of the 10-year length of the drug development cycle and by the somewhat restricted spending environment at most large pharmaceutical accounts. When drugs that are currently under development in labs that are using UPLC technology eventually make their way at volume production, we are confident that the preferred QC methodologies will transition to UPLC technology. Continuing on the chromatography front, 2012 marked the start of Waters' entry into a new separations technology that leverages the high resolving power of supercritical carbon dioxide in a high performance analytical format. We introduced our ACQUITY UPC2 platform at Pittcon 2012, and after receiving the Editors' Gold Award recognizing this system as the most innovative showcase at the conference, shipment volumes have nicely ramped through the remainder of the year. In 2013, we expect to see a positive impact of this system on our overall results, especially as UPC2 has the potential to improve analytical workflows at our customer labs while driving sales growth at Waters for not only new instruments but also associated growth in specialized ACQUITY columns and customer service plans. Well, so where do we go from here? In 2013, look for us to continue to introduce new application-tailored systems that offer more complete workflow benefits to customers. As you've seen for the past couple of years, you should expect that these systems will combine advanced mass spectrometry, ACQUITY UPLC and UPC2, our new unified operating system platform, application-specific separation chemistries and software applications. In addition, I expect that 2013 will be an exciting year for new instrument platform introductions. We have maintained a rich R&D product pipeline, and we look forward to significant launches at conferences this spring, which will showcase innovations in LC/MS and thermal analysis. In 2012, our sales and earnings growth rates were well below historical averages and our long-standing internal benchmarks. Though we are confident that generally weaker market conditions were responsible for our 2012 performance, we feel that these market conditions are temporary, and accordingly, we will maintain the same long-term internal growth targets for sales and earnings growth and manage our business to best achieve these long-term goals. We continue to believe that our technologically-focused business strategy and conservative asset allocation plan will continue to benefit our customers, employees and shareholders. Before turning it over to John, let me say that I am cautiously optimistic that 2013 will be a better year for Waters than 2012. Looking at the macro environment, the global economy appears more stable, and our outlook for business growth in nearly all geographic locations is positive. I'm also confident that our competitive position remains strong and that planned new product introductions will further enhance our competitive leadership position. Now I'd like to turn it over to John for a review of our financials and an update on the future outlook.