Greetings. Welcome to TG Therapeutics’ Conference Second Quarter 2024 Earnings Call. At this time, all participants are in a listen-only mode. A question-and-answer session will follow the formal presentation. [Operator Instructions] Please note this conference is being recorded. I'll now turn the conference over to Jenna Bosco. Jenna, you may begin.

Thank you. Welcome, everyone, and thanks for joining us this morning. I'm Jenna Bosco and with me today to discuss the second quarter 2024 financial results are Michael Weiss, our Chairman and Chief Executive Officer; Adam Waldman, our Chief Commercialization Officer; and Sean Power, our Chief Financial Officer. Following our Safe Harbor statement, Mike will provide an overview of our recent corporate development, Adam will share an update on our commercialization efforts and Sean will give an overview of our financial results before turning the call over to the operator to begin the Q&A session. Before we begin, I'd like to remind everyone that we will be making forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include statements about our anticipated future operating and financial performance, including sales performance, projected regulatory or clinical milestones, revenue guidance, development plans and expectations for our marketed products. TG cautions that these forward-looking statements are subject to risks that may cause our actual results to differ materially from those indicated. Factors that may affect TG Therapeutics operations include various risk factors that can be found in our SEC filings. In addition, any forward-looking statements made on this call represent our views only as of today and should not be relied upon as representing our views as of any later date. We specifically disclaim any obligation to update or revise any forward-looking statements. This conference call is being recorded for audio rebroadcast on TG's website, www.tgtherapeutics.com, where it will be available for the next 30 days. With that, I'd like to turn the call over to Mike Weiss, our CEO.

Thank you, Jenna and good morning, everyone, and thank you for joining us for our quarterly earnings call. I'm pleased to report that we had another quarter of outperformance across all aspects of our business, marked by the continued successful launch of our flagship drug, BRIUMVI, which was approved about 18 months ago for patients with relapsing forms of multiple sclerosis. The market response has been overwhelmingly positive and our sales performance has exceeded our initial projections. Let me start by highlighting some key achievements for the second quarter of 2024. First, on the commercial front, I'm pleased to share that we achieved $72.6 million in BRIUMVI net sales in the United States, exceeding our target of approximately $65 million, leading us to raise our full-year guidance to approximately $290 million to $300 million. That's up from $270 million to $290 million from last quarter, which was already raised from our preliminary guidance of $220 million to $260 million provided at the beginning of the year. Our commercial team has done an outstanding job in executing our launch strategy, resulting in strong initial adoption. This early success reinforces our confidence in BRIUMVI's long-term potential to reach our goal of becoming the leading treatment for relapsing forms of multiple sclerosis on a dynamic market share basis. On the R&D front, we also had a very productive quarter. While commercialization of BRIUMVI remains our core focus, we continue to explore ways to improve upon the delivery of BRIUMVI, explore potentially new indications for BRIUMVI and advance our newly acquired allogeneic off the shelf CD19 CAR T for autoimmune diseases. At the same time, we continue to evaluate opportunities to expand our pipeline. Specifically, some R&D highlights for the quarter included our ENHANCE study, which is evaluating ways to streamline the switch to…

Thank you, Mike, and good morning everyone. I'm thrilled to share our commercial progress with the second quarter of 2024. Building on the momentum from the first quarter, we have once again delivered strong performance across all key metrics, continuing our commitment to bringing BRIUMVI to patients with relapsing forms of MS. As Mike mentioned, we achieved second quarter net sales of $72.6 million, exceeding our target of $65 million, and reflecting approximately 45% growth quarter-over-quarter and 350% growth from the same quarter last year. We saw strong growth in patient enrollments with over 1,400 new patient scripts processed through the TG hub, marking a 12% increase from the previous quarter. We have now had approximately 5,850 new patient prescriptions written to our hub across 525 centers from over 950 prescribers launched to date. We are very pleased with the rate of adoption, but all three remember that since not all new prescriptions go to our TG hub, these numbers underestimate the total new patient scripts for BRIUMVI. For the second quarter, we estimate that the hub captured only about 80% to 85% of total new scripts, and as more and more academic centers and independent infusion centers adopt BRIUMVI, this hub capture rate could go down further as these types of centers are less likely to utilize our TG hub services. BRIUMVI continues to gain share in a large and rapidly growing anti CD20 market in the RMS. Strong share growth and patient adherence is leading to significant revenue growth for the CD20 class overall year-over-year. The class now represents an approximately $2 billion quarterly revenue opportunity in the U.S. with IV therapies capturing approximately 70% of that. We would expect that the class will continue to grow going forward and BRIUMVI will continue to grow within it. We…

Thank you, Adam, and thanks everyone for joining us. Earlier this morning, we reported our detailed second quarter 2024 financial results, which can be viewed on the Investors and Media section of our website. Before I get into the results for the quarter, I'd like to begin by briefly discussing an accounting matter we described in 8-K filed earlier this morning. During our second quarter review, we identified an error which was deemed to be immaterial related to the expense recognition of a single restricted stock grant from 2021. This error was isolated to 2021 and 2022 and does not impact results of operations in any other or subsequent period. Although the error was determined to be immaterial to all relevant financial statements, it was determined that this represented material weakness in the company's internal control over financial reporting related to controls around non-routine stock awards, which will require some disclosure in our 10-Q this quarter and in an amendment to our 2023 10-K that will be filed later this week. We’re already in the process of updating our internal controls relative to these equity grants and expect the material weakness will be fully remediated before December 31 of this year. Now let's turn to the financial results for the quarter. We are pleased to report that we were both cash flow positive and generated net income in the second quarter of '24. We ended the quarter with approximately $217 million in cash, cash equivalents and investment securities, up $7 million from Q1 and flat from year end. This was of course made possible by the strong quarter of BRIUMVI with $72.6 million of U.S. BRIUMVI net product revenue, which is up more than 350% over the comparable quarter in '23. Our OpEx excluding non-cash items during the second quarter came in below guided ranges at approximately $47 million, roughly in line with Q1 '24 when excluding the one-time charges seen during Q1 2024. Our OpEx for the first six months of 2024 is approximately $105 million. We're averaging just over $50 million per quarter, again, below our guided range. As discussed briefly earlier, our GAAP net income for the three months ended was $6.9 million or $0.04 per diluted share. When excluding non-cash items, net income for the period was approximately $16.4 million. And finally, I'll close by touching briefly on today's announcement of a new $250 million debt facility with Healthcare Royalty and Blue Owl Capital. We were pleased to be able to refinance our existing debt to a facility with a longer-term duration and attractive financial terms. As Mike discussed, this will provide us with sufficient resources to execute on our share repurchase program also announced today as well as continue to invest in the BRIUMVI commercial opportunity. With that, I will now turn the call back over to the conference operator to begin the Q&A.

[Operator Instructions] And our first question comes from the line of Roger Song with Jefferies.

Congrats for the strong quarter. Maybe the first one, Mike if you can comment on the current dynamic market share. As we recall, you have been say, you are getting around 10%. Just curious about this quarter and then also what's the near-term goal for the dynamic market share, understanding you want to become the number one dynamic market share in the future?

Yes, of course, our goal is to get to that number one position. We're working hard at it. We've got to have goals, so we're going to keep driving at it. Yes, I mean, look, with 1,400 out of 10,000 we're using approximate numbers but we assume again about 10,000 patients will start a new therapy, so that's the dynamic share per quarter. If you had 1,400 enrollments into the Hub, which as Adam said, probably presents probably about 80%, 85% of the total prescriptions. We are tracking toward sort of that 15%-ish range, give or take but it's not fully baked. But, yes, I think we're doing great. Team is out there hustling. They're working hard, the drug is performing well and we're going to continue to push toward our goal.

And then in terms of the allo CD19 CAR, your first indication of progressive MS. Just biologically, can you comment on how you think about the CD19 versus CD20 for this particular sub-population of the MS? And then, also when you start the trial, what are the targeted population for the progressive MS, if you're targeting certain severity or any baseline characteristics you want to do the initial study?

I mean CD20 versus CD19, I don't know that there's a huge difference in MS specifically I mean, CD19 has a broader coverage in pre B-cells going to short-lived plasma cells, which has some advantages in some areas, potentially some disadvantage in others. And that might be disadvantageous in MS if you were constantly treating these patients. Given that we think this will be a one-time treatment, or if it's not one-time, it'll be separated by a significant amount of time. I think the CD19 is quite a good approach for MS. And again, the goal for this treatment would be to have a very deep and robust B-cell depletion across tissues within the systemic system. But of course, in the in the central that would create potentially best-in-class treatment. And then you release and you hopefully let the B-cells come back. Hopefully, they're reset to be non-immunogenic B-cells and that would be ideal. And of course, you'd be able to then leave long gaps, potentially use it as a one-time treatment or very long gaps between treatment. So I think generally speaking, CD20 probably if you're going to be repeating treatments, probably CD20 a little bit better for MS. If you're looking at something that has a one-time treatment, CD19 may have some advantages in that case. You had a second part to that question, Roger, which of course I lost myself in the answer, but is there more to that question?

Just curious about the progressive MS, any specific baseline population or baseline patient characteristics you want to target in your initial clinical trial?

Not really. No. I mean, I think we're open to all progressive patients, so that is definitely the unmet medical need in MS right now. So we're excited to get into those patients. So it could be primary progressive, it could be secondary progressive, give you secondary progressive that are inactive secondary progressive that are active. We're sort of agnostic to that group. We just want to make sure we’re hitting progressive patients and hopefully, like I said, deep tissue penetration and CNS penetration would be great for that disease.

The next question is from the line of Matt Kaplan with Ladenburg Thalmann.

Congrats on the quarterly results strong results. I guess a few questions. First on the pipeline. You mentioned that you started the subcu program. Can you give us a little bit more sense in terms of potential profile of your subcu from a frequency and delivery point of view?

There is one subcu on the market. It's currently dosed once per month and I'd say relatively elegant auto-injector format. But it still needs to be taken once a month and you still have to deal with getting that drug to the patient once a month. So there's definitely logistical issues that can arise. The other that is not yet in the market, but potentially could be here in September is a subcu a version of Ocrevus. That one is a bit more clunky. You need to either have it pushed over 10 minutes to 15 minutes by a healthcare provider or used with a pump format where they attach a pump, but it will but it will cause some bruising, some swelling, some reactions, so I think that's a bit more clunky than the elegance of a subcu auto-injector. Our goal is to find ourselves somewhere in the middle, something that's less frequent than and the subcu Ocrevus will be every six months if it's approved. The goal is to have something that's less frequently than once a month and more elegant than large volume subcu that is seen with the Ocrevus. Yes, I mean, look, we think the elegance of subcu auto-injectors is the gold standard and we'd like to get ourselves there and we'd just like it to be less frequently than once a month.

And then in your prepared remarks, you mentioned along with your guidance -- increased guidance, some seasonality to expect between second quarter to third quarter versus third to fourth. Can you talk a little bit about that, how we should think about that? And then, also congrats on your first quarter in terms of achieving profitability from your underlying business. Is that something we should expect kind of going forward?

Adam, you want to take that seasonality question and then I'll come back to the profitability question.

Sure, yes. Historically, we have seen the MS market does tend to slow down a touch in the summer months. You have both patients and physicians taking vacations. So you have seen that historically and we saw it last year. So we would expect to see it this year. You also have the added with this year being a little bit unique in the ECTRIMS, the ECTRIMS conference has moved into quarter three versus quarter four last year. And we did see some softening around ECTRIMS last year with a lot of physicians from the U.S. attending that conference. So those two things we think will contribute to the guidance that we provided. But overall, we're very confident, obviously in the long-term. We've raised our full year guidance and that's just more of a seasonality that you mentioned.

And then on the profitability side, I'll take a crack and Sean's here to help and correct me if I get this wrong. But I think on an operating basis, we should maintain profitability going forward. Again, those are impacted on a GAAP basis that will be impacted or net income will be impacted by things like non-cash comp. Cash flow profitability will be impacted by things like inventory build. So we're in that sort of fringe area where some of those things will affect. But I assume as we get further into the year, we'll get closer and closer to both, regardless of whether we're buying inventory or regardless of the non-cash stuff, we'll maintain both positive net income and cash flow. But certainly on an operations basis, as you can see, the expenses, as Sean mentioned are even lower than expected. We're trying to spend it. We've added to our team. We're increasing our marketing budget. We're continuing to do that. We will continue to do that. But certainly, we don't expect that the expenses could outpace the revenue growth at this point. Sean, anything to add on top of that?

No, I think you nailed it, Mike. I think that's perfect.

Our next questions come from the line of Michael DiFiore with Evercore ISI.

Congrats on such a strong quarter. A few questions from me. Number one, like how do you foresee the initial launch of subcu Ocrevus impacting account penetration for the balance of the year? I mean, you've obviously increased guidance, but I was wondering, if you're hearing anything from the field that may have helped boost your outlook in this regard? And I have two follow-ups.

Sure. Adam, you want to go ahead and talk a little about what we're expecting from the launch of subcu Ocrevus?

Sure. Our teams are obviously will be prepped and ready for the launch of the product extension for Ocrevus. But honestly, we haven't detected a lot of enthusiasm for this product with our customer base. We've heard concerns around complex administration, nurse training required, potential side effect profile. So our interpretation today is we don't think it will have a significant impact in the U.S. market, but that's today we sit here, and that's our view from talking to many, many customers.

Second question is just any update on gross to net dynamics in Q2 and the outlook for the balance of the year, as well as if you could comment on any inventory dynamics in Q2?

Sorry, Mike, can you repeat the first part of your question?

Yes. I was wondering if you could just clarify any gross to net dynamics in Q2 and the outlook on gross to net for the balance of the year as well as comment on whether there was any inventory dynamics to be noted in 2Q.

Gross to net was similar to previous quarters and no material change and in inventory nothing to note, nothing that was unexpected.

My final question too, any update on the EU launch? I mean any feedback from large academic centers there? And have you noticed any notable differences compared to the initial rollout of BRIUMVI in the U.S.?

Mike, do you want me to take that one?

Adam, you're in a roll. Keep going.

So as you know, Mike, they launched it in Germany. We're still preparing for the launch, waiting for reimbursement in several other countries but the feedback has been very positive. They are gaining momentum, both in the academic centers but also interestingly in the community centers as well, they're getting feedback that the 1 hour infusion is particularly attractive in those centers from an efficiency standpoint. So overall, it's been going well. As far as the comparison to the U.S. launch, I think similar in that there is good uptake and enthusiasm for the product profile and we'll see how they continue to go there and we're looking forward to seeing more countries launch in later this year or early next year.

Our next questions are from the line of Eric Joseph with JPMorgan.

Congrats on the great quarter. I guess just first on the updated guidance, what is that anticipate in terms of pull through via the VA contract, I guess any sort of range you can kind of put around that. And then I'm also curious to know what kind of incremental of visibility you had this quarter on inter CD20 switching to BRIUMVI. How much switches contributed to BRIUMVI outtake? And also where you think that might go with additional data from the enhanced trial? And then secondly Mike, you kind of commented on sort of additional expenditure to support the launch here. I guess how should we be thinking about sort of the build and SG&A of the next couple of quarters? And I guess ultimately looking long-term, I guess, how should we thinking about sort of the commercial margin, the profitability of the BRIUMVI franchise?

The three part question, Eric. I think Adam, if you want -- maybe the first one was updated guidance, how it may be impacted by the VA. Do you want to start there?

The guidance includes the VA, but I would say that the VA as we -- I think we mentioned on the call last time, would not be a material impact in 2024. We're in the early stages of the launch of the VA. It's been about a month since the contract went into place. At this point, I would say 10% to 15% perhaps of the VA centers of excellence have utilized BRIUMVI. For the contract is specifically for new patients, and so I don't expect -- although our guidance includes it, it's not a major driver of the overall guidance. And then your second question was on switches from CD20. Switches from CD20 remain consistent quarter-to-quarter, we've seen a good amount of our overall patient population being switched from CD20. And we would expect with more data in the enhanced trial and making it easier to switch patients. We know that there are many patients that complain of crap gap and other issues around tolerability of other CD20s. And we believe it's an attractive market and it's been nice to see it stay consistent since launch in terms of percentage of patients switching over from CD20. And then I don't remember the third part.

I've got that one. That one was directed at me. So although you could help and chip in Sean probably, but so the question was on the launch build in SG&A and then sort of long-term where we see that going. So, I mean, look, we had a very focused strategy when we started the launch and we sized the team for that strategy. And we always said that we will grow the team and basically reinvest the revenues to build out the team. The SG&A and total OpEx for this year of $250 million baked in a growth of the team over the course of the year. We've like I said, I think since the launch, certainly in like the core field teams themselves versus sort of management level positions, we've close to doubled, I think our field force or at least grown more than 50% the field force. And that continues to grow. I mean, I get requests for new hires in the field nearly every day, certainly once or twice a week. So the team is growing, but that's, again, all baked into that OpEx number of again it's about $250 million, I'm not going to say exact and obviously we've been running a little bit below for the year so far, but I think we're still going to stick with approximately $250 million in OpEx for the year. As we move into next year, I'm confident the OpEx that we target will be higher I think incrementally higher we're certainly like I said the team will continue to grow our marketing budget we can -- we were very specific early on that we wanted to focus on clinician awareness HCP awareness and that was really a field-based endeavour, we're going to obviously continue to do that…

The next question is from the line of Mayank Mamtani with B. Riley Securities.

Congrats on a solid quarter and thanks for taking a question. So, quick two part on commercial metrics. Adam, if you could update on the persistence rate you're seeing and if you guys can qualitatively talk to an year-end market share target be it within new to class or intra class sort of switch segments and then I have a quick follow-up.

The persistence rate -- yes, the persistence rate at week 24 continues to be solid and as expected what we've said before is we expected to be around you know 80 -- high 80 and that's what we saw at least with Ocrevus and we're late in that in that ballpark so it rings very strong there. In terms of market share, I don't -- I'm not going to give a specific market share that we think we're going to hit by the end of the year. I just think to reiterate what Mike has said and what he said in the call we we're going to continue to add more and more prescribers and we're going to continue to grow in a growing market and that's what we're focused on every day, and we continue to see that we're getting traction and we'll continue to focus on doing that. And like I said, our goal is to be the number one prescribed MS therapy in terms of dynamic share.

And then at ACTRIMS, I see you're presenting an update to ENHANCE study results. Maybe just talk to what's new and incremental there and what sort of the healthcare provider feedback to the data you generated to date? And also I noticed there is a collaborative Phase 3 late breaker, GEMINI and Hercules program data coming also at ACTRIMS. We would love to hear your latest thoughts on how you're thinking the BTK drug class impact on your sort of long-range plan recognizing the results have been relatively mixed recently?

Obviously, we can't talk anything about ACTRIMS notifications and abstracts have not been released yet, so can't say anything about that. But I can answer your second part of your question about HCP feedback to the results we have presented previously. I think the feedback has been extremely positive. I think people intuitively, if they have a CD20 patient that walks in the door who is already relatively well B-cell depleted but having some other issue whether it's cramp gap or had some relapse, they don't feel that there's a need to go through the 150 milligram dose, which is in some respects a debulking dose where we take down the B-cells, so we can give a full proper dose two weeks later at 450 milligrams in 1 hour. So, I think that the people are happy to see that happy and not surprised to see that you can safely transition those patients to do that. Yes, I think that's a net positive thus far. Like I said, in the coming months, we'd like to present more data from that trial. In terms of BTK, I mean, look, I think most folks would believe at this point, regardless of whether one or several of the BTKs are successful in relapsing forms of MS, it's more likely than not to be an inferior profile to CD20s. I don't think anyone believes that they are that BTKs in relapsing forms of MS will be more active, more convenient, less side effects than a CD20 gives at this point. Again, I think that's probably now a foregone conclusion assuming that the studies in relapsing forms of MS are successful. Obviously, we've had some failures and some toxicity that we've seen along the way. We sit and we'll wait and we'll see what the data looks like, but again I think optimism is relatively low for these drugs in relapsing forms of MS. On the other side, I do think that there is a lot of excitement for the potential for these drugs in progressive forms of MS. I think in theory, if they would work in progressive MS that would be phenomenal, right. As I mentioned earlier, we're looking at [ACE] cell and progressive forms of MS because that is the unmet medical need. That's the area that is most concerning and is the least well treated at this point. So I think there is excitement and enthusiasm for it to -- if it works, I think there's certainly a fair amount of pessimism that it will work. But again, anytime you have an unmet medical need, people are enthusiastic about the potential. So we shall see again, would be a very nice thing for patients if these work in progressive forms of MS, I think in relapsing forms of MS, it's not a concern of ours.

Our next questions are from the line of Prakhar Agrawal with Cantor Fitzgerald.

Congrats on the quarter. So following-up on the subcu uptake, based on your conversations on the field, do you expect the uptake to be similar or different between academic and community centers? And for the thousand or so physicians who have prescribed BRIUMVI, do you know whether the split of their IV versus subcu CD20 is similar or different than the overall market? And then I had a follow-up.

Adam, do you want to start on the first one?

Yes. The first one is where do we think the subcu pickup will be, right? So at this point, we can go by where Roche has guided, which is in places that don't have IV infrastructure. It's tough for us to tell exactly where this will be picked up. I don't know. And as I said earlier, we just don't detect a lot of overall enthusiasm for the product. So tough to say on that. And then you asked about what the IV versus subcu -- could you just repeat that second part of the question? I want to make sure I get it right.

Yes. For the thousand physicians who have prescribed BRIUMVI so far, what's their share of IV versus subcu CD20?

Prakhar, I don't know that but we are focused on prescribers that have significant IV share. So I don't know the exact answer to your question, but I would guess that our prescribers have a higher IV share than subcu.

And just as a follow-up on BRIUMVI uptake and maybe mixed by academic and community centers, if you can provide more details around the uptake by these segments and maybe which segments are seeing the most growth right now for BRIUMVI and which segments are starting to moderate?

As we've said in previous calls, we've seen the initial uptake was in the private practices as academic centers took longer from a formulary perspective and logistics. But we've seen significant growth in all segments. And particularly in the academic centers, we continue recently in the last two quarters to add to see more and more ads from a prescriber perspective within the hospital segment. In Q2, the BRIUMVI hospital segment saw its highest ever quarter-over-quarter growth in terms of absolute vials. And now the hospital segment is the largest segment of our business today. But we're still seeing growth in both segments. And I think that's a testament to the profile of the drug and the success that we're seeing.

Our next question is in the line of Ed White with H.C. Wainwright.

Congratulations on a great quarter. So I just wanted to come back to the question on the VA contract. Adam had mentioned that it's not going to be really material in 2024. I was just wondering if you can give us your thoughts on the opportunity it represents in 2025 and beyond.

Sure, Ed. Yes, I got it. Yes, I mean, what we said was this is a -- the contract is for new patients and that will grow over time. I think the contract overall value was estimated at about $187 million for the five-year contract. I think we'll see. I think we're determined to try to get every new patient that is available and we'll continue to see how that will grow over time. We don't think compared to our overall business, we don't think it's a huge percentage. But as I mentioned, the value there is there are a lot of physicians that are in the VA that also work in academia. Our hope is that will help to have a handle effect overall in the academic setting and also reinforce the overall profile of BRIUMVI and the value proposition that BRIUMVI brings.

And Adam, as the size of that business grows over the next couple of years, is there any impact to gross-to-net?

Sure. There will be an impact to gross-to-net, for sure, given that we're -- it's public what we're -- what we offered the drug at a discount, so that will affect the gross-to-net, yes.

And perhaps my last question is just on the share repurchase program. Are you -- do you have any timelines for that? When are you going to start and any expectations of how long that program will continue to get to the $100 million?

So, we expect to get started soon. I think we'll be measured in how we do it, so it will be open market purchases, sort of like, I think [indiscernible] style of plan. And there is no fixed duration of time in which we will spend the $100 million in the repurchase. And some of it, we'll probably build in some share price targets, so we can buy more at different levels. So, yes, I think we're going to just think about it and try to buy back as many shares as we can with the money we have for the moment. Obviously, we expect that over time we'll get to reload and buy more shares, so as the revenues and cash flow continues. So, I think for the moment, we're going to just start the buying as soon as we can and we'll see how it goes.

Our final question is from the line of Corinne Jenkins with Goldman Sachs.

This is Palak on for Corinne. Just one question for us here. You touched upon seasonality for the business into the second half of the year, but could you also highlight where you see room for potential upside to your revenue guidance?

Adam, you want to take that one?

Yes, for sure. Yes, seasonality was, as I mentioned, was limited to Q3. As I mentioned that is historically affects the entire MS market, and probably disproportionately affect IV therapies just given vacation and so on and so forth. As we've noted also, we've raised the full year guidance for the year, which shows that we're confident in the overall growth story here. And I think upside would be continued growth and pick up both on the new patient side and as patients come back, we're going to start seeing the repeat prescriptions continue to grow as new patients continue to grow, and if that goes faster than we would expect, I think there's certainly potential upside.

Thank you. We've reached the end of the question-and-answer session. I'll now turn the call over to Michael Weiss for closing remarks.

Thank you. And thanks everyone again for joining us on today's call. We look forward to continuing the positive momentum into the second half of 2024. As discussed today, we'll continue to be focused on several key priorities. First, expanding BRIUMVI's reach to ensure all eligible patients can benefit from this innovative medicine. That includes building out our commercial footprint and increasing our spending on marketing efforts. Next, advancing our BRIUMVI expansion initiatives through our subcutaneous development, our enhanced switch study and exploring new indications for BRIUMVI. Finally commencing our Phase 1 for azer-cell and progressive MS as well as looking at opportunities to expand our pipeline. With that, I'd like to close by thanking the patients and clinicians that put their trust in TG and BRIUMVI and our loyal shareholders for their support and once again the whole TG team for making it happen. Have a nice day.

This will conclude today's conference. You may disconnect your lines at this time. Thank you for your participation.