Jess Jankowski
Analyst · Anthony Rubin
Thank you, Michelle. Good morning to all of those listening live, and welcome to those who choose to listen later online. I'm glad you could join us for our Third Quarter Investor Call. Today's discussion will cover current results, the current state of the business and our plans for 2022. Kevin Cureton, our Chief Operating Officer, will be joining me today on the call.
It's hard not to be excited about our progress in 2021. Our strategy, our investment of time, focus and financial resources have helped us to finally achieve our long-standing goal of becoming an exciting company. We brought our companies to the point where business development and sales growth are not our biggest challenges anymore. The markets want what we've developed, and we continue to see demand grow through 2022 and beyond.
I invite you to contemplate something. The greatest challenges we're facing today involve enhancing and expanding capacity, managing working capital and adding top people to our team. These are addressable challenges that following with those that all fast-growing businesses deal with. There are known ways to solve these things and they involve a degree of patience, proper management of financial resources and applying known solutions. What a great spot to be in. Over the past 2 years, there hasn't been any appreciable slowing of the trends we've been seeing toward broader consumer acceptance of and demand for minerals-based skin health products.
We remain optimistic about the future of our Solésence finished products business and about the growing demand for minerals-based products and ingredients generally. Before I expand on this, let's cover some numbers. Unless identified otherwise, all numbers will be stated in approximate terms. Our Q3 2021 revenue was $7.9 million, up 104% or $4 million when compared to the record revenue of $3.9 million for the same period last year.
9-month 2021 revenue was up 80%, topping $22 million compared with then record revenue of $12 million for the same period in 2020. For the third quarter of '21, earnings were $1.4 million or $0.03 per share. This was up $900,000 or $0.02 per share quarter-over-quarter. For the 9 months in '21, earnings were $2.7 million, coming in at $0.06 per share, representing an increase of $1.9 million or $0.04 per share over 9-month 2020 numbers.
2020 may not have been that long ago, but we're a different company today. We now have a multiple. Solésence products are still the driving force behind our growth, and I'll start there. We've had $13.4 million in Solésence sales for the first 9 months of '21 compared to $6.7 million for all of 2020 and $1.9 million for 2019. I'll leave it to Kevin to discuss specifics on what's been driving our Solésence growth and how we plan to expand it by continuing to develop new products and new customers a bit later in the call.
Our personal care ingredient sales, which we often refer to as Active Pharmaceutical Ingredients, or APIs, have seen nice growth so far in '21, and we expect growth to continue in '22. We had $5.3 million in API sales for the first 9 months of '21 compared to $4.2 million for the same period in 2020. APIs are still an important part of our business. We expect solid Q4 volume, and we think we'll get back to the $8 million to $9 million annual range in 2022.
Before we discuss medical diagnostics and life sciences, the third strategic part of our business, I wanted to take a few minutes to explain the macro environment driving the growth, both in our Solésence business and now of our API or Ingredients business. While the 2 areas are very different in terms of our customer base and our growth expectations, many of the same forces are fundamental to our value in both markets.
Nanophase and Solésence are companies that have pioneered the use of zinc oxide is not only safe, but also aesthetically pleasing alternatives to chemicals-based products. The markets we serve have seen mineral-based sun and skin health products, driven largely by zinc oxide as a critical API, continue to see good demand growth. Minerals have dominated growth in both active and daily wear sunscreens in leisure wear and cosmetics.
They've also proven to be a bright spot for the Prestige Cosmetics markets. Consumers want comfortable and safer ways to look great and to protect their skin from environmental damage, much of which comes from the sun's rays. Regarding our plan for Solésence, we saw a record growth in sales throughout the COVID-19 pandemic. We like where we position ourselves and feel great about our strategy. In addition to the high-quality of our products and their good performance in protecting and enhancing skin health, the series of external things happening in the marketplace continues to help us expand our product advantages.
You may recall that over the past several years now, some of the most common chemical sunscreens have been banned due to their environmental impacts. They are not considered safe for use in your coral reefs. Many of our downstream API customers and all of our Solésence customers have seen that consumers everywhere landlocked or seaside have drawn their own conclusions. They don't like the thought of endangering themselves or the environment. Additionally, the Food and Drug Administration's pronouncements on sunscreen API safety, the first proposal to review these ingredients in decades continue to pressure the industry to either prove the safety of chemical sunscreens or eventually withdraw them from the market.
There were 16 active ingredients listed in what the FDA calls the monograph or the list of active ingredients allowed to be used in human sun care in the United States. Of the 14 chemicals-based APIs on this list, the FDA has declared 2 of these ingredients unsafe for humans and the other 12 to require much more data to be submitted to prove them safe for use on humans. Combined, those 14 active ingredients represent all of the APIs currently allowed in the monographs and the class that we refer to as being chemicals based.
They also represent our most significant market competition, and they make up 14 out of the 16 total ingredients included in the monograph. Zinc oxide and titanium dioxide, the 2 remaining options in the current monograph, are the only 2 that the FDA has deemed to be safe for human use. Both are the only minerals-based APIs. That's what we make, that's what people want, and that's what we sell.
While the industry is pushing back, the FDA has gone to atypical lengths to hold the chemicals-based manufacturers accountable. They need to prove that their products are safe or pull them from the market. This will continue to unfold over the next few years, and we expect this to continue to be a positive for us in the marketplace. Regardless of the near-term FDA outcome, consumers have been listening to all of this and reacting to it. Many have decided they aren't going to wait on the FDA, so they're demanding more minerals-based products on their own. We are in a great spot to take advantage of what we think will be a growing than possibly permanent shift in these markets.
Moving on to our third and final strategic area of focus, medical diagnostics and related life science applications comprise this part of our business. These sales reside in our Advanced Materials product category. This category also includes all of our legacy products for architectural coatings, surface treatment and polishing. We had $3.4 million in Advanced Materials sales for the first 9 months of 2021 compared to $3.7 million for the same period in 2020.
The great majority of sales in this category represent medical diagnostics. The COVID-19 pandemic greatly accelerated our sales in this space during 2020 and for the first half of 2021. We saw a drop-off in medical diagnostics ingredient sales for Q3 of this year and do not expect any significant sales in Q4. While we don't expect near-term demand to reach the same levels as we've seen over the last couple of years, we do expect demand in this area to continue to exceed historic levels, which prior to 2020, we're generally in the sub-$1 million range annually.
We also believe that the type of testing our major medical diagnostics customer does called polymerase chain reaction or commonly PCR testing has become a critical use of our technology in the life science space. It is our view that the current expanded testing environment, regardless of the specific virus to be targeted, signals a trend toward greater acceptance of this practice of testing as a normal part of our lives. While it's difficult to predict to what extent COVID-specific demand will impact growth in this area going forward, we have demonstrated some important things with our ingredients here. We believe that our deep expertise in material science has created advantages that enable performance in certain tests that may not be achievable through other materials.
This is why we've elevated our development in this area to become our third major strategic focus. To recap, these 3 strategic areas are in order of expected near to midterm growth, Solésence fully formulated products, Active Pharmaceutical Ingredients for sun and skin care and medical diagnostics ingredients. While we still sell some legacy products in the architectural coatings and polishing space, these volumes are relatively low, and we're not doing any further product or market development in this area.
Again, we're about skin health products and ingredients and medical diagnostics. These are the areas where we see the greatest demand and the areas where we believe we offer the greatest value. Now I'd like to introduce Kevin Cureton, our Chief Operating Officer, to discuss progress in these strategic areas and its drivers in more detail.