Ladies and gentlemen, thank you for standing by. Welcome to the Quantum-Si Second Quarter 2023 Earnings Call. [Operator Instructions] Please be advised that today's conference is being recorded. I would now like to turn the conference over to Juan Avendano, Head of Investor Relations for Quantum-Si. Juan, please go ahead.

Good morning, everyone. Thank you for joining us. Earlier today, Quantum-Si released financial results for the second quarter ended June 30, 2023. A copy of the press release is available on the company's website. Joining me today are Jeff Hawkins, Chief Executive Officer; and Jeff Keyes, Chief Financial Officer. Before we begin, I'd like to remind you that management will be making certain forward-looking statements within the meaning of federal securities laws. These statements involve material risks and uncertainties that could cause actual results or events to materially differ from those anticipated. Additional information regarding this risk and uncertainties appears in the section entitled Forward-looking Statements of our press release. For a more complete list and description of risk factors, please see the company's filings made with the Securities and Exchange Commission. This conference call contains time-sensitive information that is only accurate as of the live broadcast today August 7, 2023. Except as required by law, the company disclaims any intention or obligation to update or revise any forward-looking statements. During this call, we will also be referring to certain financial measures that are not prepared in accordance with U.S. Generally Accepted Accounting Principles or GAAP, including EBITDA and adjusted EBITDA. A reconciliation of these non-GAAP financial measures to the most directly comparable GAAP financial measures is included in the press release filed earlier today. With that, I will turn the call over to Jeff Hawkins.

Thank you, Juan. Good morning, everyone, and thank you for joining us. In today's call, we will provide a business update to present our second quarter financial performance and provide an outlook for the remainder of 2023. We will then open the line for questions. As a reminder, the goal of Quantum-Si is to bring next-generation in sequencing to every lab, everywhere. Our proprietary technology delivers deeper unbiased proteomics insights that we believe will accelerate scientific research, enable the discovery of new biomarkers and ultimately power the development of new therapies and diagnostic tests that will positively impact human health. While we continue to make solid progress with our commercialization activities in the second quarter, we experienced some challenges that prevented us from meeting our revenue expectations. First, early customer feedback identified a set of software features that were important for our customers to efficiently analyze and interpret their experimental data. Second, we experienced some customer implementation challenges due to the wide range of biological sample types, sample preparation methods and sequencing applications customers wanted to perform with our technology. Finally, we observed some general extension to the sales cycle as the internal purchasing process at our customers has slowed down from what we experienced in the beginning of the year. I would now like to provide more color on each of these items as well as share other updates on our progress during the quarter. Our first corporate priority is to commercialize Platinum, Carbon and the 2M chip. Our commercial organization build-out is well underway. Under the leadership of our Chief Commercial Officer, Dr. Grace Johnston, we are building a truly world-class team across sales, marketing and customer support. Despite experiencing some implementation challenges in the quarter, our commercial team collaborated closely with customers to resolve the challenges and…

Thank you, Jeff. First, I would like to say how excited I am to be on board with Quantum-Si. We have an excellent leadership team and all of us are aligned and focused on commercial execution and delivering the best and most innovative solutions to our customers. I personally come from a background of leading a series of companies through rapid change in growth and where extreme financial discipline was paramount. I plan to draw upon these experiences to help lead Quantum-Si through a continued financially disciplined approach that ensures we utilize our existing capital in the best way for rapid commercial growth, while at the same time, maximizing our capital runway. Now let's discuss the details of our Q2 2023 financial results. Revenue in the second quarter of 2023 was $205,000, which consisted of revenue from our Platinum instrument and associated consumable kits. At the end of the second quarter, we had two units that were in backlog and revenue was deferred. We anticipate recognizing revenue on these units in Q3. Gross profit in the second quarter was $78,000 and gross margin was 38%. Our gross margin will be somewhat variable for the near future as we work through our initial stages of commercialization and also be impacted by the timing and mix of instruments versus consumable sales. GAAP operating expenses in the second quarter of 2023 were $27 million compared to $30.2 million in the second quarter of 2022. The decrease was primarily due to a $2.6 million lower research and development expense and $600,000 lower SG&A expenses. Included in those amounts is a decrease of stock-based compensation by $1.9 million, with the remaining $1.3 million comprising large decrease in general and administrative expenses, offset by higher sales and marketing expenses as we ramp up our commercial operations team. Net loss for the second quarter of 2023 was $25.6 million compared to $32.4 million in the second quarter of 2022. Adjusted EBITDA for the second quarter of 2023 was a loss of $22.9 million compared to a loss of $25.8 million in the second quarter of 2022. The reconciliation table of adjusted EBITDA to GAAP net loss is provided in our press release filed earlier today. As of June 30, 2023, we had $297.2 million in cash and cash equivalents and investments in marketable securities. Our guidance for the rest of 2023 includes our controlled commercialization execution approach as we align our R&D resources towards capabilities and feature enhancements that have the broadest customer appeal. Finally, I am reiterating that our non-GAAP operating expenses are expected to be flat compared to 2022, while still ensuring that we have all the resources and capabilities for our commercial execution plan and our existing cash, cash equivalents and investments in marketable securities will provide runway into 2026. Now I'll turn the call back over to Jeff Hawkins for closing remarks.

Thank you, Jeff. Over the last quarter, we made great strides in the build-out of our commercial team and have received valuable feedback from customers as we continue our thoughtful and controlled commercialization of Platinum. We believe the outcome of our strategic review of R&D will better position us to deliver additional product improvements before the end of 2023, while also ensuring a pipeline of technology improvements that will support a steady cadence of releases throughout 2024. Going forward, we will continue to be laser-focused on delivering the technology capabilities and applications customers want most, while maintaining a high level of fiscal discipline over the use of our capital resources. Operator, please open the line for questions.

[Operator Instructions] The first question comes from Kyle Mikson with Canaccord.

So Jeff, appreciate all the, I guess, commentary around like, I guess, what's been happening lately and why the revenue came in where it is and why you're kind of doing some of these initiatives now and what's going to be happening going forward like the software and implementation of sales cycle stuff. But I guess, like obviously, less revenue than last quarter, you put up $0.25 million in revenue last quarter on almost $0.5 million in orders. Maybe that makes some sense given there was likely pent-up demand early in the launch. But I guess like why weren't you able to convert those orders exiting 1Q into revenue or at least generate more revenue than the last quarter? Again, like $0.5 million in orders exiting the quarter just kind of interesting. And then maybe, Jeff, could you just share any comments on the orders, like the dollar number of orders in second quarter and the backlog exiting the quarter as well?

Yes. Thanks, Kyle. I'll take your -- the last part of the question first. So we exited the quarter, as Jeff Keyes said, with two instruments in the backlog that we would expect to convert in the third quarter. With respect to sort of events during the quarter that impacted revenue. As I said in the prepared remarks, it had a lot to do with just some of the implementation challenges that we experienced with customers. And when we experience these things, we react sort of in real time, meaning we deploy our applications team to help those customers validate a given sample type or validate a sample prep method they're using and we don't want to sort of keep expanding the installed base and end up in a situation where we're unable to provide the level of support needed. So we had to sort of measure our activities on the commercial front to ensure we could really provide that high level of support on the implementation front.

Okay. I mean that's -- yes, that's helpful. And again, it sounds like some of the changes that you're making are going to be done by the end of the second quarter. I mean, are you -- is it safe to say that in the second half or I guess by the end of the year, a lot of these -- I'll use the word issues, but they're just kind of like bumps and growing pains, I guess that will happen along the way. Those will be worked out by the end of the year and you'll kind of at least enter the fourth quarter or '24 at like a solid run rate you'll be comfortable with?

Yes. Kyle, I think that's a fair way to assess it. We're learning a lot every day in the market. We're prioritizing the various improvements that customers want to see or the applications that they'd like us to open up or help them optimize. We're deploying people in real time to these activities, as I mentioned in the prepared remarks, we'll go even further with that, with the sort of the finalization of the R&D strategic review. I mean the goal is to have sort of been the smoothest implementation sort of area we can be in for 2024. But even saying that, we do expect that we'll continue to evolve and enhance the product for the foreseeable future. There's a lot of headroom technologically here to continue to expand the capabilities and enable our customers to do more and more, and we'll continue to invest in that.

Okay. And then -- and Jeff Hawkins, you talked about last quarter how you -- there could be a potential inflection in orders and shipments and revenue in the second half of this year. I guess it sounds like that's not really expected anymore, but could you just provide some thoughts and maybe Jeff Keyes as well and welcome to the call. Maybe you could provide some thoughts on how to think about, I guess, shipments and revenue and utilization, things like that in the second half of the year as we sort of think about modeling.

Yes. So I'll start and Jeff Keyes can add any color he'd like to add. As I mentioned in the prepared remarks, Kyle, we're going to keep the sort of the controlled launch in place through the end of the year. That doesn't mean that there might not be some uplift in revenue in a given quarter, but we don't expect sort of a rapid acceleration in the second half, a much more sort of controlled launch in the second half with the growth. Jeff Keyes, anything you want to add to that?

No, I think that about sums it up. Jeff's comments are consistent with my thoughts as we work through this process, the R&D realignment and deployment, we're going to continue to have this controlled ramp. But we would expect that we might see some uplift over the next couple of quarters, but I think that's going to be dependent on our customer base and how we interact with them for the rest of the year.

Okay. And then on the strategic R&D realignment, it sounded like just Carbon for now. I mean maybe Jeff, just can confirm that. I feel like maybe there were probably some chips in development that were higher density, maybe like that's affected. And with Carbon, like was that critical to any orders like were they contingent on Carbon being launched and perhaps that was like a guaranteed bundle? I'm just kind of curious about that. And then overall, again, not -- I'm just not totally certain on this right now. What was the purpose of the strategy kind of underlying the review? And kind of like what's the end game here? And how would you -- what would you deem as a successful outcome for that?

Yes. Kyle, let me take a shot at those if I miss one, let me know. First, on the Carbon front. So there are -- there were no deals in the pipeline that were contingent upon a Carbon. We didn't have any sort of Carbon bundles as you described it. Really, the assessment of Carbon was about is a cartridge-based sort of solution, which can be very elegant, but has a lot higher sort of development sort of cost and time lines to adapt it to all of these different sample types and sample methods is that the best way to approach sample prep or is more of an open platform, one of the commercially available liquid handling platforms. Might that be more flexible to sort of range of sample types and methods we're seeing. So that's really that what that evaluation is about. And that's the only program, as you mentioned, that we're stating right now is on hold. We're obviously though, reviewing, Kyle, the totality of the R&D investments and really looking at driving the investments that really unlock the full potential of the Platinum device and the existing consumable. What we're seeing is there's a lot of growth potential for that existing platform in chip. And it's really about enabling applications. It's about enabling additional sequencing capabilities as we expand coverage and other things like that. So really, that's how we're looking at it. And then the end game is ultimately that we have the right level of R&D investment into those core areas that will really drive the adoption and that we have that sort of process that allows us to generate a consistent sort of release of improvements throughout a given year. So that's really the endgame in mind.

Yes. And you touched on all the questions there. Can I just ask about manufacturing? I mean, you didn't really mention that at all, but is that a bottleneck whatsoever so far? Or are you pretty much good to go on when it comes to supply chain, things like that?

Yes. No concerns on supply chain. And manufacturing was not a bottleneck in any way to the results in the second quarter.

Okay. Awesome. And then maybe just closing on like a positive comment. Look, it's good to hear the outbound marketing that's kind of all systems go, and it sounds like early success there, early kind of like progress. When you kind of crank that up, I mean, are you thinking about going after any new customer types, maybe you're going to unlock or increase your footprint in nonacademic markets like biotech, maybe just kind of expanding your footprint there, I think that'd be kind of interesting to hear?

Yes, Kyle, thanks for that question. The way the commercial marketing team is approaching, it's a mix. Sometimes you're diving in with a campaign to really look for a specific type of user with specific types of applications within the academic research environment. And other times, the campaigns will be around unlocking new segments, Biotech, as you mentioned, perhaps more industrial settings for antibody QA/QC. So really, the outbound marketing programs are very, very targeted. So we'll run many of them across these different areas as we try to drive really that specific demand that lines up well to where we're seeing success in the market.

The next question comes from Yuan Zhi with B. Riley.

Jeff, a quick follow-up on Kyle's question. You mentioned the challenge in the implementation front. Can you comment on if the test launch requests from customers or potential customers have changed since 1Q? And then I have a follow-up question.

Yes. The requests haven't changed, Yuan. Really what it is, is more you get into the customer's laboratory and they work through that full workflow from their -- from whatever the biological sample type is they selected on up through the sequencing on our platform and ultimately, that analysis and there's just a very broad range of samples and sample prep methods. I mean ranging everywhere from someone who might isolate a protein in a gel and cut out a band to people using immuno-precipitation kits and other sort of chemistries. So it's not really that there's any difference in the request. It's just each customer has a somewhat unique set of samples and prep methods that we have to work closely with them to optimize in front of the sequencing on the Platinum instrument.

Got it. Thanks for clarifying the technical challenge there. My other question is, can you maybe talk about the poster presentation you had at ASMS? What was challenge on identifying protein and proteoform in that sample in that presentation?

Yes. At the ASMS conference, that was really a poster to not only demonstrate some of the capabilities of our technology, but really to help for that group of users who are also mass spec users really help them understand how does our technology perform in comparison to mass spec as well as share information around the workflow, the automated analysis that our platform affords a user. So it was really an educational and sort of comparative data study for that -- for those users in the mass spec community.

The next question comes from Swayampakula Ramakanth with H.C. Wainwright.

Good morning, Jeff and Jeff. Appreciate you taking my questions. So, Jeff, the issues that some of your current customers have flagged during this initial launch. Were they to a specific sample types, is it more universal?

Yes. I wouldn't say it's a specific sample type as much as it is just this combination of sample type and the way they're preparing the sample, how many proteins are they looking for at once, how pure is that sample versus how impure that sample. It really wasn't about a specific sample type that was challenging.

Okay. And then in terms of the software upgrade that you released, if I heard it correctly, it was in July. So do you think that upgrade was able to handle the issues at hand? And how have the customers responded to that upgrade to date?

Yes. Good question. So you are correct. We released that software version in July. And I would say the key attribute that customers were looking for were some additional visualizations at the amino acid level of the data they were generating with the technology. So the initial version showed paratopes of peptides, how peptides are indicated in to a given protein. And really what this new software did was really enhance the UI of that, the ability to visualize it, giving amino acid level data and information, sort of in aggregate, things that allowed our customers to really understand the data they were generating really at both the amino acid, the peptide and the protein level. So again, we rolled that out in July. The feedback from users has been very positive. They're very happy with those changes and with sort of the overall improvement the user interface. And as we get more feedback, we'll continue to make enhancements to that software. But I think the big sort of transformation of our software that needed to take place to customers on the analysis side, is this change we made in July, and it will be somewhat more incremental moving forward.

Okay. And then just my last question. This is on the sales cycle lengthening that you stated. Is this more of -- because at this point, most of your customers are from academic labs. Is it more academicians waiting for the fourth quarter to ensure that the use of all the research dollars associated with the grant? Or is this more than that? Is this some really accounting and other people getting involved in it?

Yes. Okay, we're not hearing that there's a scenario where our instrument is being held up because there's some pending grant that hasn't been approved. Really, what we're commenting on in the prepared remarks is, given Grace and [indiscernible] and other members of the commercial team sort of experience with an instrument at $70,000, we would expect if that enters the procurement cycle out of a customer, it's going to take some period of time to get through that process. And what we're seeing is we've gotten through the sales cycle with the customer, the sort of the technical buyer that purchase order goes into the procurement process, and that process is just moving a little bit slower. It's not moving through that process of internal approvals and more of the procurement and accounting or financial side as fast as we had been seeing. So again, no reason to believe at this stage that those instruments that are in that cycle won't ultimately be approved and will come through. It's just moving at a slower pace than sort of we saw in Q1 and sort of a slower pace than we would expect given our collective experience selling capital equipment in the life science space.

I show no further questions at this time. I would now like to turn the call back to Juan for closing remarks.

Thank you all for your participation today. We look forward to updating you on our progress in the next quarterly earnings call. Have a good day.

This concludes today's conference call. Thank you for participating. You may now disconnect.