Christian Henry
Analyst · Cowen. Please go ahead.
Yeah. I mean, I think, we're going to try to, I mean, realistically, we're going to try to stay out of, looking at backlogs and order books in the snap, but to color, what's happened since a year end. We've had two very, very, very successful conferences, the plant and animal genome conference AGBT. And if anything, the funnels are strengthening the perspective lots of customers or many customers have actually run samples inside of our labs now in our – in our applications labs. So, customers are getting more confidence around, it really is what we say it is. And I think that's really – that's really exciting. And so the, the funnel is it continues to strengthen. It is a global. It is a global funnel, and there are a lot of new customers. And I think that's one thing that's really important to me is, not only do we want to get all of our existing customers to scale up with Revio, but it is really important for us to show new customers and see these new customers get engaged with the technology. So far, I think the – I think we've seen a lot of that internally, with our customers and perhaps maybe most interestingly is the scale people are starting to talk about is different than ever before in the history of PacBio. And so people are starting – people are contemplating, 10,000 sample projects, 20,000 sample project, larger scale, large-scale transcriptomic projects, large-scale whole genome projects. And I think that's going to be – that's extremely encouraging to, kind of prove out the thesis that we needed to get to higher throughput, and we needed to get to economics that enable that through -- enabled scale. We already -- and we continue to do with the best accuracy and has that all of us preprint showed, quite frankly, the HiFi sequencing right now is the most accurate and most complete sequencer you can get. And so that's all been really well, I know that doesn't help you build your model per se, but anecdotally, it makes us feel a lot better. I didn't understand, Dan, your question really on guidance barriers on Sequel II, maybe could you ask that question again?