Good day, everyone and welcome to today’s program. At this time all lines are in a listen-only mode. However later in the program you will have the opportunity to register to ask a question. Today’s conference will be recorded and at this time it is my pleasure to turn the program over to Kevin Gorman. Please go ahead sir.

Thank you very much and welcome everyone to our third quarter earnings call. I am joined with Chris O’Brien, our Chief Medical Officer; and Tim Coughlin, our Chief Financial Officer. Before we started Jane, could you read our Safe Harbor statement?

Good afternoon. I want to remind you of Neurocrine’s Safe Harbor caution. Certain statements made in the course of this conference call that state the company’s or management's intentions, hopes, beliefs, expectations or predictions of the future are forward-looking statements, which are subject to risks and uncertainties. Information concerning factors that could cause actual results to differ materially from those contained in or implied by the forward-looking statements is contained in the company’s SEC filings, including but not limited to the company’s Annual Report on Form 10-K and quarterly reports on Form 10-Q. Copies of these filings may be obtained by visiting the Investor Relations page on the company’s website at neurocrine.com. Any forward-looking statements are made only as of today’s date and we undertake no obligation to update these forward-looking statements to reflect subsequent events or circumstances. Kevin?

Thank you, Jane. Tim if you could go over the Q3 financials and year-to-date performance.

Sure, thanks, Kevin. And good afternoon everyone. Thank you all for joining us. Today after financial markets closed we released our third quarter 2013 financial results. Our loss for the third quarter was $0.17 per basis common share outstanding compared to $0.05 loss in the third quarter of 2012. Year-to-date our loss is $0.53 versus $0.07 for the first three quarters of 2012. These financial results are consistent with the results of the first two quarters of 2013. When comparing both the quarter and year-to-date 2013 results to those same periods in 2012 the major contributing factor to the change in net loss when comparing the two was a reduction in revenue earned under the collaboration agreements with both AbbVie and Boehringer Ingelheim. The active participatory portion of both of these collaborations ended as planned during 2012. Revenue for the third quarter was consistent with the first two quarters of the year at $700,000. Our revenue for the year will be $2.9 million. Research and development expense increased year-over-year primarily due to increased efforts around our VMAT2 program and general administrative expenses relatively unchanged across all the periods presented. We’ve remained in a very strong financial position ending the month of September with over $158 million in cash, investments and receivables. As part of the quarterly release we have updated our guidance for 2013. This is due primarily to three items. The results of our Phase IIb Kinect study which served to move certain cost into 2014, ongoing cost mitigation efforts and an increase in stock option activity which increased our year-end projected cash balance. We now expect to have net loss for 2013 of approximately $46 million to $47 million. Our 2013 expenses should approximate $53 million to $54 million. As a result of the previous mentioned stock option activity and the lower anticipated expenses we now expect to end the year with over $145 million in cash, investments and receivables. With that I’ll turn it back over to Kevin and will entertain any financial questions during the Q&A.

Thank Tim. Before I turn it over to Chris O'Brien to talk about the work that we’re doing with our clinical and research programs I’d just like to state that AbbVie had its earnings call yesterday. They reiterated again that they are on track with the Phase III endometriosis trial, the first of the two Phase III trials that they have ongoing. And they say second half of ’14 is when they’ll have top line data on that. And that they have the ongoing Phase IIb in uterine fibroid. We’ll be happy to take any questions you have on that program. But now Chris you want to take over?

Yeah, thanks Kevin and good afternoon. Thanks for participating in the call. Since our last call we’ve been intensely focused on several activities around the VMAT2 program. The first priority has been to complete the recruitment and the randomization into the Kinect 2 study and we have been successful in doing so. We closed screening for this program when we reached 203 subjects. Our goal, as you may recall, was to randomize 90 subjects and we had anticipated approximately a 50% a screen fail rate which will give us our target. But as you recall in our Kinect study the screen fail rate was slightly higher at the end. So we allowed screening to go to just over 200 subjects. And in fact the screen fail rate was about 50%. So we ended up randomizing 102 subjects into the Kinect 2 trial and that’s why we are happy to have a slight over randomization in the subject number. We’ve been very happy with the conduct of the Kinect 2 study so far. The protocol and the investigational drug appear to be well tolerated. We had a low discontinuation rate. It’s a little under 20% to-date. And the drug appears to be well tolerated. We’re at a fairly low reporting of adverse events. Obviously we are blinded but we certainly know who was randomized, whether they were bi-polar subjects or schizophrenia or schizoaffective disorder subjects. And it appears that the adverse event reporting rate is approximately the same in the mood disorder bi-polar population as it is in the schizophrenia/ schizoaffective population. Obviously we are stratifying randomization to placebo or active drug based on underlying diagnosis. So we take this reporting of AE to be a good indication that the mood disorder subjects are tolerating 98854 as well the schizophrenia/schizoaffective disorder…

Thanks, Chris. So I am open for your questions at this point in time.

(Operator Instructions). Very good, we’ll go first to the side of Sara Slifka with Morgan Stanley. Your line is open. Please go ahead.

Hey guys, thanks for taking my question. I just had a couple of quick ones on Elagolix. Just regarding the second trial it looks like on clinicaltrials.gov, that trial is listed as having a 12 months extension like the first trial. Do you have a sense as to whether the extension in the second trial is going to be needed for approval? And then secondly there was initial talk about the possibility that the EMA might want to put active control trial, do you have any sense as to whether the two Phase III Elagolix trials satisfy both the U.S. and the EU. Thanks.

Thanks Sara, so this is Chris. My understanding of the second endometriosis trial is that 12 months follow-up period is the potential for follow-up that the bulk of the off drug safety follow up will come from the first pivotal trial, which is primarily the U.S. trial. The second trial is a multi-national, smaller in size and not meant to be weight limiting. So I think the option there is that if it's needed, based on data from the first trial that obviously it's available but I don’t think it's [written in stone]. And as far the EMA that’s something that you’d have to ask AbbVie what their intent is there. Obviously most endometriosis, most European trials for which there is a comparator, an active comparator trial is generally sought by EMA. But in this case AbbVie has not been specific as to their plan, these efforts these two pivotal trials that are going on are meant to support the most important market opportunity which is here in the U.S.

Great, thank you.

(Operator Instructions). We’ll go next to Bob Hazlett with ROTH Capital. Your line is open.

Thanks, thank you for taking the question. My question is regarding 854 and the question is with the low rate of AEs you’ve seen in Kinect 2 and the dose escalation data, does that bolster any thinking regarding moving towards the consideration of a higher dose as you move toward the Kinect 3 studies on with 854, thanks very much?

I think that’s a great question and that is exactly the kind of information we seek to get out of the Kinect 2 study. If you do the simple arithmetic 100 patients, 80% of them escalate the first time and then 80% of those escalate the second time. You are going to have a spread of subjects at 25, 50 and 75 milligrams and it may well be that the exposures that we get at those doses have been optimized and we have a PK/PD model we can plug into that will help us understand whether there is potential utility or even need to explore higher doses. We certainly have some room to look at higher doses in terms of tolerability as well as pre-clinical safety margin and we can build that into our next study if we want to. So the other interesting thing obviously is I am very keen on seeing the week 12 data. If you go back to the clinical literature about the only other VMAT2 inhibitor that's been used in hyperkinectic movement disorders the tetrabenazine you know that most of the clinical articles published by experts like Jankovic and others have been 12 twelve week trials. And so they are seeing their most robust effect after a few months of treatment and there is some indication that in fact you have a cumulative benefit over time, at least based on that literature. I am very keen to understand is there a difference between week two, week six, week eight and week 12 in our twelve-week trial, because in fact if you have that good tolerability and accumulation of benefit at even the lower doses that could obviously help us very much in selecting doses for subsequent trials. So December will be a key month for us to get that data from both the titration and the twelve week Kinect study.

And just one quick follow up with that, would you expect to announce both those results together?

I am not sure we’ll be so lucky. I think the Kinect 12 data will come slightly ahead of Kinect 2, -- Kinect 12-week data will come slightly ahead of Kinect 2, in late in December so obviously we’ll get that out as soon as we can.

Thank you for the color.

And we have no further questions at this time. I would like to turn the call back over to our host.

Thank you very much. Thank you all for joining us this afternoon. As you can see that we continue to be in a very secure cash position. We have well over three years of run rate in the bank. And there is a wealth of data, that as Chris has putted out here that’s going to be coming through in just the next several weeks, that we are going to be able to utilize in all the programming all the planning is being done now, so that we can put these into our models and understand our drug even that much better so that we can design the next series of studies that are going to take place in this. So I want to thank you once again for your attention and we look forward to meeting you in meetings in the rest of the year. Bye-bye.

And this does conclude our presentation today. Ladies and gentlemen, thank you for joining us. You may disconnect at any time and have a great day.