Good day ladies and gentlemen, and welcome to the Second Quarter 2014 Geron Earnings Conference Call. My name is Crystal, and I'll be the operator for today. At this time all participants are in a listen-only mode. Later we will conduct a question-and-answer session. (Operator Instructions). I'd now like to turn the call over to your host for today Ms. Anna Krassowska, Head of Investor Relations. Please proceed.

Thank you, Crystal. Good afternoon, everyone, and thank you for joining us for the Geron second quarter 2014 earnings call. With me today are Dr. John Scarlett, our President and Chief Executive Officer; and Olivia Bloom, our Executive Vice President, Finance and Chief Financial Officer. This afternoon, we issued a press release that reported results for the second quarter ended June 30, 2014. This release can be found on our Web site at www.geron.com. Today's call is also being webcast live on our Web site and will be available for replay through September 12. Before we begin, please note that except for statements of historical facts, the statements during this conference call are forward-looking statements under the Safe Harbor provisions of the Private Securities Litigation Reform Act of 1995. These include, without limitations, statements regarding the timelines, prospects and plans for imetelstat, including anticipated timelines for submitting data to the FDA to address the of our clinical hold, the FDA's listing of our clinical hold, time lines and plans for the IND and IST transfer from Mayo Clinic, and Geron clinical study initiation obtaining positive safety data, the therapeutic potential and safety of imetelstat and financial or operational projections or requirements, including spending guidance and completion of payment of any dividend in connection with the Asterias transaction. These statements include risks and uncertainties that can cause actual results to differ materially from those in such forward-looking statements. Additional information concerning factors that could cause actual results to differ materially from those in the forward-looking statements is contained in Geron's periodic reports filed with the Securities and Exchange Commission under the heading Management's Discussion and Analysis of Financial Conditions and Results of Operations, and Risk Factors, including in Geron's quarterly report on Form 10-Q for the quarter ended June 30, 2014. Undue reliance should not be placed on forward-looking statements, which speak only as of the date they are made, and the facts and assumptions underlying the forward-looking statements may change. Except as required by law, Geron disclaims any obligation to update these forward-looking statements to reflect future information, events and circumstances. We'll begin today's call with a summary of the second quarter operating results from Olivia, and then Chip will review recent events and our activities to address the full clinical hold on our IND. Olivia?

Thanks Anna, good afternoon. For the second quarter of 2014, we reported a net loss of $8.7 million $0.06 per compared to $8.9 million or $0.07 per share for the comparable 2013 period. Revenues for the second quarter of 2014 were $341,000 compared to $112,000 for the comparable 2013 period. The increase in revenues was due to the receipt of license fees from new research use only licenses for Telomerase. Interest and other income for the second quarter of 2014 were $99,000 compared to $56,000 for the comparable 2013 period. The increase in interest and other income primarily reflected higher cash and investment balances. We ended the second quarter of 2014 with $147.6 million in cash and investments. We have not incurred any impairment charges on our investment portfolio. Total operating expenses for the second quarter of 2014 were $9 million compared to $9.1 million for the comparable 2013 period. Research and development expenses for the second quarter of 2014 were $5.2 million compared to $4.8 million for the comparable 2013 period. General and administrative expenses for the second quarter of 2014 were $3.9 million compared to $3.4 million for the comparable 2013 period. Operating expenses for the 2013 second quarter also included restructuring charges of $838,000 in connection with our decision to discontinue our discovery of research program, and close our research laboratory facility in April 2014. The increase in research and development expenses for the 2014 second quarter compared to the same period in 2013 was primarily the result of higher cost for the manufacturing imetelstat. This increase was partially offset by reduced personnel related costs and other research costs resulting from previous restructuring and the discontinuation of our Discovery research program. The increase in general and administrative expenses for the three months ending June 30, 2014 compared…

Thank you, Olivia. Good afternoon, everyone. I would like to start with the discussion of the status of Dr. Tefferi's investigative-sponsored trial in patients with myelofibrosis that’s being conducted at the Mayo Clinic. That trial which we call the myelofibrosis IST was initiated under an investigator-sponsored IND, which is separate from Geron's IND for imetelstat. The myelofibrosis IST was placed on a partial clinical hold shortly after our IND was placed on full clinical hold. To resolve the clinical hold on his IND, Dr. Tefferi was required to provide follow-up information regarding reversibility of hepatotoxicity for all patients who received imetelstat in the myelofibrosis IST. In June, we were very pleased to report that the FDA had removed the hold on Dr. Tefferi’s IND following his submission of a complete response to the agency. We reported previously that prior to the partial clinical, there were 45 patients receiving imetelstat in study. Based on the enrollment data reported by Mayo Clinic as of July 15th, 33 of the 80 enrolled patients were continuing to receive treatment with imetelstat, 23 including 23 of 62 enrolled patients with MF 1 out 9 enrolled patients with last phase MF and all 9 out of 9 enrolled patients with the subtype of myelodysplastic syndrome or MDS known as refractory anemia with ringed sideroblasts or RARS. Last week we announced an agreement between us and Mayo Clinic that will transfer to Geron the IND under which the myelofibrosis IST has been conducted. Under this agreement, we will also issue sponsorship for the myelofibrosis IST. The study will continue to be conducted at the Mayo Clinic and Dr. Tefferi will remain as the principal investigator. We and Mayo Clinic have agreed to a plan targets to transfer the IND and sponsorship responsibility for the conduct of the…

(Operator Instructions) Our first question will come from the line of Cory Kasimov from JPMorgan. Please proceed.

Hi, guys, this is actually Whitney on for Cory. First question is, I guess you said with the 1Q 2015 as early as timing in mind, you said you'd be submitting all the data you mentioned to the FDA. Is that expected in 3Q, 4Q? Can you give us any more granularity on the timing there?

Yes, we expect to respond by the end of 2014 to the FDA and that will include clinical information regarding LFT abnormalities and the incidents reversibility of those abnormalities in Geron’s sponsored trials of imetelstat while was in Tefferi’s Myelofibrosis IST and we would expect to submit those data in an integrated assessment of the LFT observations in the context of the overall safety and efficacy in relative on that medical needs and patients populations being treated with imetelstat. So we think that providing this context to the enabled and informed assessment of the benefit, this profile for imetelstat treatment in patients with high unmet medical needs such as that they characterized as myelofibrosis.

Got it. And then, second question, I guess, on the last call, you guys had mentioned some work being done on an EU strategy. Any updated thoughts there or potential timing of moving forward, if at all?

Yes, in fact, we did look forward to that and I think that based on what we have found out we’re currently focusing primarily on our response and first on our response to obtain the FDA’s permission to hold on IND for imetelstat or to permit extra study imetelstat under a partial clinical hold.

Our next question will come from the line of Charles Duncan from Piper Jaffray. Please proceed.

Hi, guys, it's Roy in for Charles. Thanks for taking the question. So, Chip kind of touched on this, but I guess the 1Q timeline sounds pretty quick. I just wonder if you guys could characterize the -- I guess the extent and quality, in your mind, of the data you were able to get for the ET and MM patients? I'm guessing it must be decent, given the -- what seems like a kind of quick timeline. Thanks.

Well, that’s pretty much the timeline, Roy, that we had laid out when we first started this exercise, so I do think there are any that I aware of any significant changes in it. We have been working really hard at this and I think that it was a relatively strong effort on our part obviously to get that, so I would agree with that. And so I feel like this is our expectation, if for some reasons we’re not able to meet that obviously we’ll update people.

Okay. Can you give us any indication of what proportion of patients you were able to get data for? The majority?

No, like we’re still in process of retrieving data and patients and I think we really shouldn’t be characterizing the LFT data at this time, that’s going to be between us and FDA, and when we’re a position to be able to comment about what actual outcomes of those discussions then we’ll happy to discuss it with you.

Our next question will come from the line of Brian Klein from Stifel. Please proceed.

Thanks for taking my questions. In regards to the Tefferi Mayo Clinic IST study, can you give us a flavor for the patients that have come off of that IST in terms of whether they are dropping out of the study due to any off-target effects or safety concerns? Or -- and if any of those patients have maintained their responses?

Unfortunately Brian that is the exact topic of discussion in the abstract that I was put in and so it’s really under the embargo policy of ASH at this point. So I don’t think we’re going to be able to make any comments at this time about it. I am sorry.

Okay, no problem. In terms of your ET study, where all the patients are now off-therapy, can you give us a sense of whether any patients have remained transfusion-independent?

So in the ET study all of the patients were required by FDA to come off of therapy. And so we were following up their experiences predominately, if they had LFT abnormalities, we are following up what happened to those LFT abnormalities after seeing the real focus of our efforts with them.

Our next question comes from the line of Thomas Yip from MLV & Company. Thomas Yip - MLV & Co.: Thank you very much for taking my questions. Just have two short questions about the IND transfer. So I was just wondering did the IND transfer trigger any payments to Mayo Clinic? Or are there any future royalty obligations?

We haven’t disclosed any of the context of this or any financial arrangements between us. So I think I am going to remain silent with regarding that eventually I suspect some of these will be made public, although I am not sure what will be active.

This is Olivia. I will just characterize in general that once the IST of the clinical studies moved to Geron’s sponsorship it will be treated just as all other company sponsored trials where the company will be sponsoring the sites through support of clinical operations as well as funding for patient treatment as they go through this protocol. So in that sense they would be treated just as any clinical site in our regular company sponsored trial. Thomas Yip - MLV & Co.: Okay, thanks. Yes, and I understand that some information cannot be disclosed yet. So we're also wondering how much would it cost for Geron to take over the IST to, I guess, to finish the IST at this stage? How much in total?

Well that’s a bit difficult to project because obviously it depends how long the patient stay in the trial and obviously how many patients end up staying in the trial itself. But I would just like to say that we have been supporting the IST historically, so our support obviously will continue financially going forward. So at this time I am not updating guidance for 2014, because of this IND transfer or this assumption or responsibility with IST.

Our next question will come from the line of Charles Dunkin, Piper Jaffray. Please proceed.

Hi, it's Roy again. Just -- sorry for the follow-up, but I have a dumb question -- but did your IND cover myelofibrosis? And if not, do you think this transfer would have occurred even without the hold? Thanks.

So our IND never had a myelofibrosis protocol submitted to it or conducted under the ages of our own Geron IND. And so the ability to gain access to the full flavor of the data from the myelofibrosis IST was really an important consideration in our planning. So we work very hard with Mayo Clinic to transfer the IND for that purpose to get access to the full information and so forth.

And with no further questions in the queue, I would now like to turn the call over to Dr. Scarlett for closing remarks.

Thank you all very much. We appreciate the support for the Company during these challenging times and look forward to being able to share more and good information with you sometime in the future hopefully. Thank you all very much.