Tom Joyce
Analyst · Derik De Bruin of Bank of America, Merrill Lynch
Sure. Let's take in there. But let me give it a shot. So let's have a key – first of all, we continue to be really impressed with the GE team, we mentioned that when we announced the deal, that we found that coming through due diligence. But as we normally do with large acquisitions, we put a transition team together, we acquired – the soon to be acquired business has a transition team. And so, we continue to get some exposure to that team and we remain really impressed by them, it's a highly passionate and talented group with great industry experience. As you saw in Q1 from them the business is off to a great start in 2019. What we've heard a little bit is just sort of very anecdotally that things continue to track quite well. Their first quarter was – at core growth above where they've been in the last couple of years. So all indications are the business is in wonderful shape. From a transaction standpoint, we issued the equity in Q1. Clearly, the debt financing ought to be helped by what we're seeing now in lower rates, assuming those kind of hold in both the U.S. and Europe and that's just in comparison to when we announced the deal. So overall, we feel very good about where we are. No change to our expectations. We've had good and constructive dialog with the regulators and we're working with them like we would on any other deal. And so we're continuing to drive toward a fourth quarter close and feel good about that. Relative to your second question, which was around small molecule versus large molecule cell and gene therapy, and profitability, and then you made specific reference to Zolgensma and the recent introduction of that breakthrough product by the division of Novartis, your question was really around profitability, I guess. First of all, going back to the core, we've always seen good profitability in our business around small molecule related applications and large molecule. I would say no difference. Obviously as we continue to develop breakthrough new products associated with the evolution of biological drug discovery, development and processes, we continue to focus on enhancing gross margins, as we drive new product development and so obviously the value that we deliver to shareholders is directly associated back to the gross margin that we're able to achieve. And so we continue to really keep the long horizon in mind, in terms of what the market needs are, and continue to drive products that will help to enhance gross margin, which they've done. And so we feel good about that. Now, when it comes to cell and gene therapy, it's so early in the evolution of that market today, that it's hard to say anything that's particularly material or quantitative around overall profitability, even our iCELLis product line, which is doing exceptionally well. It's still early days and its market penetration as fast as that pickup has been and as unique of that product is in the market. So more to come over time, but in general, our outlook is profitability looks very solid across this market. Zolgensma as you mentioned, you probably know from what's been publicized is a unique therapy, is a breakthrough, it's incredibly impactful to children under the age of two, and it's a very costly therapy. And that's a challenge in healthcare today is the cost of developing therapies and so on. But that's a dynamic that where quite a number of steps removed from when it comes to drug pricing and the relationship with the payers. And so I think the continued evolution of the technologies associated with these breakthroughs is going to be imperative for our customers today and we're proud to be a part of it, but we certainly recognize the challenges that are associated with how costly these have become. Just one last point, that many of you have probably heard me say that at Danaher, we have a, what we call our shared purpose and it's four simple words, helping realize life's potential, whether that's the potential for our associates or our customers, our shareholders. Ultimately in many respect patients and there's probably no better example of how we help realize life's potential when it comes to healthcare than when a tool of ours can play a role in really impacting the quality of life for patients. So we're proud to be a part of that and there is more to come and it's still early days.