John Nicols
Analyst · Craig-Hallum. Your line is now open
Thanks, Bruce. Good afternoon everyone and thank you for joining us. I’m proud to report another quarter of exceptional financial results by Codexis. Net income was $1.4 million on revenues reaching $14.9 million, which included $4.1 million in product revenues. When introducing 2016 revenue guidance, we noted our expectation for growth and product revenue as key component. It’s gratifying that year-to-date, our product revenues have increased by more than 60% versus last year. Growth in product sales indicates the momentum of our engineered enzymes the increasingly utilized in our customers’ processes. Our third quarter revenues also included $8 million in milestone revenue earned from the successful technology transfer of our CodeEvolver protein engineering platform to Merck. As with the successful tech transfer to GlaxoSmithKline, we satisfied Merck at every step in the process and successfully completed the transfer ahead of schedule. We continue to show exceptional execution for transferring the technology to our CodeEvolver protein engineering platform licensing partners, noting that each individual tech transfer is customized for the given partner. As a result of our strong performance, we are reporting our second consecutive quarter of profitability. We also have gained greater visibility on full year revenues as we move towards the end of the year, allowing us to raise the low end of our previous revenue guidance range. We now expect revenues to be between $47 million and $49 million, representing growth versus 2015 of 12% to 17%. If delivered as expected, Codexis will have delivered its third consequent year of double-digit revenue growth. Solid sustained financial results like these can only flow from proven business approaches that generate value for both shareholders and clients. Our traction with engineering novel proteins that improve manufacturing processes and reduce costs for the major pharma clients is remarkable as we close 2016. Highly visible pressures to reduce drug pricing for these clients is making cost reduction a growing imperative, and Codexis is increasingly being called on to help on that. Seven out of the top 10 largest pharmaceutical companies are working significant programs with us in the final two quarters of 2016, seven out of the top 10. Referencing Contract Pharma’s top 25 pharma and biopharma report published July, August 2016 as well as the current Codexis pipeline posted on the Investors section of codexis.com. Let me give you a feel for the exciting broad progress we are now making with large pharma. First and foremost, let me start with Merck, as the depth and breadth of our relationship with them is the blueprint by which we desire to drive all other major pharma relationships. Merck is one of our CodeEvolver platform licensees, a major commercial user of Codexis enzyme for a blockbuster drug and that expanses continuous user of Codexis R&D with the aim to drive lower costs more widely across its drug pipeline. In the third quarter with Merck, we number one, completed the CodeEvolver license tech transfer and recognized an $8 million milestone payment; number two, delivered $1 million plus sales of the enzymes to Merck’s blockbuster Januvia diabetes drug franchise; and number three, lined up and began operation of several new dedicated R&D project teams for their growing list of protein engineering targets. Note that these new dedicated R&D project teams lined up in the third quarter are on top of an already running set of dedicated project teams. Each of these R&D teams running in parallel at Codexis are focused on different protein engineering targets. Merck sees how widely applicable our protein engineering approach can be to improve their drug manufacturing processes. Merck is not alone. Also in the third quarter, we delivered multi -- I’m sorry, we delivered $1 million plus commercial product sales to another top 10 pharma company’s commercial drug manufacturing process. We finished a six-digit enzyme improvement project for a third top 10 pharma company, with aim to improve their recently launched drugs manufacturing route. We lined up a six-digit clinical product order batch for 4Q to a fourth top 10 pharma customer for a Phase 1 oncology drug. We are finishing in 4Q a six-digit enzyme improvement project on a late stage Phase 2/3 clinical drug candidate for our fifth top 10 pharmaco. And we broke open a set of enzyme improvement RFPs for yet a sixth top 10 drug company. This one, a company we had never done any material business prior. And finally, number seven with GSK. I’m delighted to report that in 3Q, we recorded our first project specific milestone revenue from GSK under the backend economics of our CodeEvolver licensing agreement. This collaborative project use CodeEvolver to develop an enzyme to optimize a new biocatalytic process for one of GSK’s drugs already on the market. This is the first instance of what we believe will be a series of growing backend revenues from our CodeEvolver licensing partnerships. Clearly, we are building momentum with large pharma clients. But that’s not the only place we are successfully applying our CodeEvolver protein engineering technology. In the biotherapeutics arena, we were pleased in 3Q to be advised that our biopharmaceutical partner exercised its option for a non-exclusive license to a novel enzyme developed by Codexis. The enzyme was developed using CodeEvolver for use in one of the partner’s preclinical therapeutic development programs. We collected a modest annual payment from them in 3Q and expect those annual payments to continue and potentially grow in the future. In addition, we are advancing the development of our own pipeline of biotherapeutic assets. Advancements have been made on animal trials and pre-IND planning for our overall biotherapeutic candidates for phenylketonuria disease. We have started early stage animal trials on the second therapeutic enzyme for a different disease condition and have begun discovery efforts for a few other disease targets. All these targets are well-suited to have our CodeEvolver protein engineering deliver against. And finally, our efforts outside of pharma continued to progress as well. By year-end, we expect to finalize the third funded R&D chapter of our work with our second food industry partner. In addition, we have advanced our self-funded enzyme development project for a food ingredient with wide industrial interest. And we are approaching the launch of an enzyme that we have been developing for a wide set of potential customers in a new industry outside of pharma and food. Our pipeline of projects is diverse, growing and satisfying a very significant set of the world’s leading companies. CodeEvolver protein engineering is delivering value in our target markets and creating a stronger, growing company for our shareholders we invested in. With that, I’d like to turn the call over to Gordon for a detailed review of our financial performance. Gordon?